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Endocrine Effect Articles & Analysis: Older
18 articles found
A number of the emerging contaminants associated with having a harmful effect on the endocrine system have been recognized as endocrine disrupting chemicals. The endocrine system is a network of glands and organs that produce, store, and secrete hormones in the body. ...
ByCoftec
So, what are endocrine disruptors (ED)? They are chemicals that may interfere with the endocrine (hormonal) system and thereby produce harmful effects in both humans and wildlife. ...
Little attention has focused on the effects of androgenic endocrine‐disrupting chemicals (EDCs) on amphibians. The present study aimed to investigate the effects of lower concentrations of the androgenic EDC 5α‐dihydrotestosterone (DHT) on gonadal differentiation and development in Pelophylax nigromaculatus, a true frog distributed widely in East ...
The chemical UV filter benzophenone‐3 (BP‐3) is suspected to be an endocrine disruptor based on results from in vitro and in vivo testing. However, studies including endpoints of endocrine adversity are lacking. The present study investigated the potential endocrine disrupting effects of BP‐3 in zebrafish (Danio rerio) in the ...
This paper reports on short‐term fish reproduction assays in zebrafish and fathead minnow conducted to examine the potential for methyl tertiary butyl ether (MTBE) to cause effects on the endocrine system. Both studies were performed under Good Laboratory Practice and in accordance with OECD and USEPA test guidelines. ...
The authors studied the effects of thiram, a fungicide used for seed coating with known effects as endocrine disruptor. ...
Interactions between insulin signaling and steroidogenesis suggest potential endocrine‐disrupting effects of metformin found in the aquatic environment. ...
As knowledge of contaminants capable of adversely modulating endocrine functions increases, attention is focused on the effects of synthetic progestins as environmental endocrine disrupters. In the present study, effects of exposure to a synthetic progestin (norethindrone, 168 ± 7.5 ng/L) and endogenous progestogen ...
The environmental fate and transport of steroid growth promoters suggest potential for endocrine disrupting effects among ecological receptors; however, the initial excretion of steroid metabolites from cattle administered growth promoters has not been well characterized. ...
The aim of the present study was to investigate the effects of the androgenic endocrine disruptor 17β‐trenbolone on the sexual development of zebrafish (Danio rerio) with special emphasis on the question whether adverse outcomes of developmental exposure are reversible or persistent. ...
PAHs and their metabolites have carcinogenic and endocrine disrupting effects in human and wildlife, and can have serious consequences. ...
Here, we examine the endocrine and physiological effects of short‐term, acute exposure of environmentally relevant concentrations of analytical grade atrazine in juvenile barramundi (Lates calcarifer) in a controlled laboratory experiment. Expression of hepatic vtg was not affected supporting previous studies that atrazine does not have a direct estrogenic ...
Pharmaceutical and personal care products (PPCPs), some of which have endocrine disrupting effects at environmentally relevant concentrations, have been detected in many surface waters. We evaluated the effects of two common endocrine disrupting PPCPs on the life history traits of the snail, Physa pomilia, using a life table ...
In the present study, we investigated the endocrine disrupting effects of di‐(2‐ethylhexyl)‐phthalate (DEHP), on the Chinese rare minnow (Gobiocypris rarus), an endemic fish distributing upstream waters in the Yangtze River. ...
Various aquatic bioassays using one of several fish species have been developed or are in the process of being developed by organizations like the US Environmental Protection Agency and the Office of Economic Cooperation and Development for testing potential endocrine disrupting chemicals. Often these involve assessment of the gonad phenotype of individuals as a key endpoint ...
Perfluorooctane sulfonate (PFOS) is a widespread and persistent chemical in the environment. We investigated the endocrine‐disrupting effects of PFOS using a combination of in vitro and in vivo assays. ...
Effect‐directed analysis (EDA) can be useful in identifying and evaluating potential toxic chemicals in matrixes. Previous investigations of extracts of sediments from the upper Danube River in Germany revealed acute nonspecific and mechanism‐specific toxicity as determined by several bioassays. In the present study, EDA was used to further characterize these sediments and identify groups of ...
Exposure to these substances under some circumstances is believed to result in adverse developmental, reproductive, neurological, and immune effects in both humans and wildlife. Over the years, researchers have pointed to a growing list of anomalous health effects (including the feminization of certain male wild fish and male reproductive disorders in humans) ...