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Neonatal Articles & Analysis: Older
26 articles found
Human brain has approximately 171 billion cells, of which slightly more than half (approximately 86 billion) are nerve cells. These 86 billion nerve cells are a diverse cell population with hundreds of specialized types and functions, but all originate from three neural cell lineages--neurons, oligodendrocytes and astrocytes. All three cell lineages originate from a pool of neural stem and ...
Recombinant protein drugs are therapeutic protein drugs produced using DNA recombination technology or other biotechnologies. Compared to traditional low molecular synthetic drugs, they have the advantages of strong specificity, low toxicity, and significant therapeutic effects. However, as biological macromolecular drugs, recombinant protein drugs also have issues such as short half-life, easy ...
Doctors and nurses have long relied on tried-and-true medical technologies to care for their patients, but the ever-increasing focus on patient safety has made innovation in this field a priority. One growing technology is the use of marker bands, which are platform agnostic data capture tools (e.g., barcodes or RFID) used to monitor patient conditions accurately and efficiently. Through its ...
Anti-G reactivity in red cell antibody detection and identification studies mimics the presence of both anti-D and anti-C. This can complicate decision making in pregnant patients. It is important to determine if anti-D is present for guiding Rh immune globulin prophylaxis. ...
Pregnancy and childbirth are critical moments in the life of a woman, marking the beginning of a new chapter in their lives with the arrival of a newborn. While most pregnancies and deliveries occur without significant complications, there are instances where the health of the mother, the baby, or both could be at risk. In such critical situations, blood transfusions can be a lifeline, ensuring ...
Abstract Background: Preeclampsia is a major pregnancy complication that results in significant maternal and infant mortality, most of which occurs in low and middle-income countries. The accurate and timely diagnosis of preeclampsia is critical in management of affected pregnancies to reduce maternal and fetal/neonatal morbidity and mortality, yet difficulties remain in establishing the rigorous ...
Human brain has approximately 171 billion cells, of which slightly more than half (approximately 86 billion) are nerve cells. These 86 billion nerve cells are a diverse cell population with hundreds of specialized types and functions, but all originate from three neural cell lineages--neurons, oligodendrocytes, and astrocytes. All three cell lineages originate from a pool of neural stem and ...
AdvaitaBio’s IPathwayGuide plays significant role in the research of a Stanford investigator. Stanford University is one of the world’s leading research and teaching institutions. With a 1.69 billion dollar annual sponsored research budget, Stanford has been delivering breakthrough discoveries in numerous domains. For over 6 years, Dr. Linda Yip has been conducting research at ...
Abstract Objective Noise in the neonatal intensive care unit can be detrimental to the health of the hospitalized infant. Means of reducing that noise include staff training, warning lights, and ear coverings, all of which have had limited success. Single family rooms, while an improvement, also expose the hospitalized infant to the same device alarms and mechanical noises found in open bay ...
The combination of congenital heart disease (CHD) and respiratory distress syndrome (RDS) can present a difficult scenario to manage with conventional mechanical ventilation (CMV). Our patient presented with poor right ventricular (RV) function, and refractory respiratory failure on CMV. High-frequency jet ventilation (HFJV) was used in order to improve ventilation at a similar or lower mean ...
Introduction Incidence of caesarean section performed at full dilatation is increasing. Delivery can be technically challenging and associated with increased maternal and neonatal morbidity. The objectives of this study were to evaluate local caesarean section rate at full dilatation, assess the indications, review the maternal and neonatal morbidity and identify any training ...
Background Several pioneering studies have provided evidence for the introduction of universal pulse oximetry screening for critical congenital heart disease. I lowever, whether the benefits of screening reported in studies from high-income countries would translate with similar success to low-income countries is unknown. We assessed the feasibility and reliability of pulse oximetry plus clinical ...
Objective: To reduce exposure to hyperoxia and its associated morbidities in preterm neonates. Study design: A multidisciplinary group was established to evaluate oxygen exposure in our neonatal intensive care unit. Infants were assigned target saturation ranges and signal extraction technology implemented to temporally quantify achievement of these ranges. The outcomes bronchopulmonary ...
Pediatric Short Bowel Syndrome (also called SBS or Short Gut Syndrome) generally develops shortly after birth due to an underlying gastrointestinal (GI) condition. The condition then can lead to intestinal surgery, in which part of the short bowel is removed. SBS is a devastating condition where patients struggle to absorb life-sustaining nutrients from their diet due to the surgical removal of ...
B Medical Systems deployed thousands of its medical refrigeration solutions to support the COVID-19 Vaccine Cold Chain in Ghana. The country of Ghana, situated between the Ivory Coast, Burkina Faso, and Togo, has successfully carried out many vaccination campaigns since 1978 when the country adopted the Expanded Programme on Immunisation (EPI). Since then, there has been a decrease in cases of ...
Founder and CEO, Agustin Fernand of Rational Vaccines that is developing a vaccine for herpes. There is a pandemic raging across the world – and it has nothing to do with a coronavirus. Approximately 500 million people worldwide suffer from genital herpes. Several billion more have an oral herpes infection. Herpes is a life-altering disease that can lead to chronic pain, blindness, and ...
Overcoming issues of heterogeneity in disease classification and enabling new approaches to successful drug development. SLE is an autoimmune disease with a wide range of clinical manifestations. It affects approximately 5 million people worldwide and its prevalence varies in different geographies. SLE accounts for around 70% of all cases of lupus, other forms being cutaneous lupus, ...
In clinical work, wristband checking is one of the important ways of patient identification, and plays an important role in strict implementation of the checking system. Especially for severe patients, neonates and infants with surgery, coma, unconsciousness and disability, wristband should be worn as the basis for effective checking. And hospitalization number is the only sign that patients do ...
Abstract Reactive astrocytes are associated with every form of neurological injury. Despite their ubiquity, the molecular mechanisms controlling their production and diverse functions remain poorly defined. Because many features of astrocyte development are recapitulated in reactive astrocytes, we investigated the role of nuclear factor I-A (NFIA), a key transcriptional regulator of astrocyte ...
Abstract Fibronectin in the vascular wall promotes inflammatory activation of the endothelium during vascular remodeling and atherosclerosis. These effects are mediated in part by fibronectin binding to integrin α5, which recruits and activates phosphodiesterase 4D5 (PDE4D5) by inducing its dephosphorylation on an inhibitory site, S651. Active PDE then hydrolyzes antiinflammatory cAMP to ...
