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Antigen Human Articles & Analysis: Older

8 articles found

CD19: One of The Most Important Targets for Car-T Cell Therapy

CD19: One of The Most Important Targets for Car-T Cell Therapy

The Structural Composition of CD19 The human CD19 antigen is a 95 kd transmembrane glycoprotein that belongs to the immunoglobulin (Ig) superfamily [1-2]. ...

ByBeta Lifescience


CD Genomics Perspective: Bioinformatic Analysis for HLA Genotyping

CD Genomics Perspective: Bioinformatic Analysis for HLA Genotyping

Introduction to HLA Human leukocyte antigen (HLA) is a 3.6 Mb segment on the short arm of chromosome 6 that contains over 200 genes. It is also known as the major histocompatibility complex (MHC), and it is the most polymorphic region in the human genome, involving diverse immune reactions. HLA is divided into HLA-class I (corresponding to MHC ...

ByCD Genomics


The ins and outs of TCR-T cell therapy   

The ins and outs of TCR-T cell therapy  

TCR-engineered T cells express tumor antigen-specific receptors with alpha and beta chains generated from high-quality, high-affinity clones of antigen-specific T cells. ...

ByCreative Biolabs


Recombinant Cyno NKG2A & CD94 Heterodimer

Recombinant Cyno NKG2A & CD94 Heterodimer

Product name NKG2A and CD94 heterodimer (KLRC1), recombinant protein Full Product Name Recombinant human NKG2A and CD94 heterodimeric protein (N-8His and N-DYKDDDDK) Product synonym names Heterodimer NKG2A and CD94; Heterodimer KLRC1 and CD94; CD159A and KLRD1 heterodimer Product gene name Recombinant protein KLRC1 3D structure ModBase 3D Structure for P26715 Host: ...

ByGBI - Genera Biosystems Ltd.


Synthesis of high aspect ratio gold nanorods and their effects on human antigen presenting dendritic cells

Synthesis of high aspect ratio gold nanorods and their effects on human antigen presenting dendritic cells

The biocompatibility of high AR NRs was evaluated on primary human monocyte derived dendritic cells (MDDCs), and compared with that of spherical gold nanoparticles (NPs) and low AR NRs. Low AR (~4.5) gold NRs induced considerable cell death due to CTAB, while spherical gold NPs (7 nm) and high AR (~21) gold NRs showed no or minor effects on viability and immune regulatory ...

ByInderscience Publishers


Identification and analysis of epitope-based malarial vaccine targets using computational biology

Identification and analysis of epitope-based malarial vaccine targets using computational biology

A combination of bioinformatics approach and computational tools are used to screen and select antigen sequences as potential T-cell epitopes of supertype human leukocyte antigens (HLAs) alleles. ...

ByInderscience Publishers


Envelope-based HIV vaccine peptides as antigens in HIV-1 immunodiagnostics

Envelope-based HIV vaccine peptides as antigens in HIV-1 immunodiagnostics

Many HIV-1 envelope-based synthetic peptides behave as antigenic mimics of linear or conformational epitopes generated in vivo in infected subjects, meaning they can be used as immunogens for antibody induction in appropriate animal models or as antigens in Enzyme-Linked Immunosorbent Assay (ELISA). These peptides are linear or branched, single sequenced or ...

ByInderscience Publishers


Preclinical and safety studies of V-1 Immunitor

Preclinical and safety studies of V-1 Immunitor

Thus V1 is safe and the risk of toxicity or adverse events is negligible compared to the clinical benefit.Keywords: AIDS immunotherapeutics, toxicity, safety, antigens, magnesium, mucosa, human immunodeficiency virus, HIV, food supplements, immunogens, preclinical studies, V-1 Immunitor, V1, ...

ByInderscience Publishers

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