Antitumor Immune Response Articles & Analysis: Older
2 articles found
Cytokines-mediated signaling is a primary way of immune system communication. The common gamma-chain family of cytokines is a set of six cytokines that signal through the common cytokine γ chain receptor (γc/CD132/IL2RG). These cytokines include IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Besides the IL-2RG receptor subunit, the γc family cytokine receptors include IL-2RB ...
” This translational study analyzed patient tissues, preclinical models and retrospective data to determine how the IL-6 T helper 17-cell (Th17) pathway is involved in toxic responses and can be inhibited to separate inflammatory autoimmune responses and antitumor immunity reaction. ...