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Autoimmune Disease Articles & Analysis: Older
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Recombinant protein drugs refer to protein products that originate from animals and plants and are developed through biotechnology research. These protein drugs exhibit certain biological activity and can prevent, diagnose, and treat diseases in humans, animals, and plants. Compared with small molecular drugs, recombinant protein drugs offer advantages such as high activity, high specificity, and ...
Gene editing has emerged as a transformative tool in the field of biomedical science, with significant implications for the treatment of various diseases. The primary focus is on harnessing this technology for modifying primary T cells, a type of white blood cell crucial for the immune response. This approach has opened new avenues for immunotherapy, providing hope for treating conditions like ...
Antibody drugs are a kind of drugs that treat diseases through artificially synthesized antibodies, achieving therapeutic purposes by specifically binding with target molecules. Common types of antibody drugs include monoclonal antibodies, artificially synthesized antibody fragments, immunotoxins, antibody-drug conjugates, etc. Antibody drugs have shown remarkable therapeutic effects in the ...
Peptide drugs are bioactive protein fragments composed of short chains of amino acids. Due to their high efficiency, specificity, and relatively low toxicity and immunogenicity, they occupy an important position in modern medicine and drug development. They have shown great potential in treating various diseases, such as cancer, autoimmune diseases, infectious diseases, and metabolic disorders. ...
Antibody drugs are a type of drugs that treat diseases through artificially synthesized antibodies, which bind specifically to target molecules for therapeutic purposes. Common types of antibody drugs include monoclonal antibodies, artificially synthesized antibody fragments, immunotoxins, and antibody-drug conjugates, etc. Antibody drugs have shown significant therapeutic effects in the ...
Sialic acid proteins are a special type of glycoproteins, characterized by the presence of sialic acid at the end of the sugar chain. Sialic acid is a biologically important sugar molecule that plays a crucial role in many intercellular interactions, including cell recognition, adhesion and signal transduction. Therefore, the detection of sialic acid proteins holds significant value in disease ...
Plasma proteomics is an emerging field of science dedicated to the analysis and understanding of the protein composition in the plasma and its functions. Plasma, as one of the most abundant biological fluids in the human body, contains tens of thousands of proteins, reflecting the health status, disease process, and treatment response of the body. Therefore, plasma proteomics holds great ...
Antibody drugs, as a breakthrough in biotechnology, are now widely used in the treatment of various diseases, including cancer, autoimmune diseases, and infectious diseases. These drugs are usually precisely designed protein molecules that can specifically bind to targets in the human body, such as specific molecules on pathogens or diseased cells, thereby guiding the attack of the immune system ...
When it comes to the fascinating world of proteins, some names like collagen or hemoglobin might ring a bell. But what about tenascin-C, more commonly known as TNC protein? This often-overlooked molecule plays a vital, if subtle, role in how our cells talk to each other. Let's delve into the remarkable story of TNC protein and why it deserves more of the spotlight. What is TNC Protein? Before ...
Peptide drugs are bioactive molecules composed of multiple amino acids connected by peptide bonds. Typically, they are made up of 10~100 amino acids, with a relative molecular mass less than 10,000. Most peptide drugs are derived from endogenous peptides or natural peptides, so they have little or no side effects on the human body. Compared with protein drugs, peptide drugs also have advantages ...
Peptide drugs are bioactive molecules formed by connecting multiple amino acids through peptide bonds. Generally, they are formed by connecting 10-100 amino acids, with a relative molecular mass lower than 10000. Most peptide drugs come from endogenous peptides or natural peptides, so they have no or little side effects on the human body. Compared to protein drugs, peptide drugs also have ...
Drug antibody testing is a laboratory testing method specifically designed to evaluate the immune response of the human body to certain drugs. This test is commonly used to monitor a patient's immune response to biological agents or other drugs, especially in the treatment of chronic diseases such as autoimmune diseases, certain cancers, and inflammatory diseases. The principle of drug antibody ...
T cells are the most numerous and functionally complex type of lymphocytes, mainly including CD4+ T cells and CD8+ T2 cells, which play an important role in cellular immunity and assist in humoral immune response. According to their functions in the immune response, T lymphocytes mainly include helper T cells (Th cells), regulatory T cells (Treg cells), effector T cells and cytotoxic T cells. ...
The development of monoclonal antibodies (mAbs) has completely transformed the field of medicine, providing targeted antidotes against a wide range of diseases, including cancer, autoimmune and infectious diseases. These therapeutic antibodies aim to specifically target antigens on the surface of cells and bind to them, leading to acidic reactions that result in the destruction of target cells. ...
In the vast and intricate world of biology, the development of proteins and antibodies stands as a crucial field of study, driving advancements in medicine, biotechnology, and beyond. From the fundamental building blocks of life to the complex molecules that defend our bodies, these remarkable biomolecules hold the key to unlocking new frontiers in scientific understanding and practical ...
Abstract Background: Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation of synovial joints. Anticitrullinated protein autoantibodies are detected by the CCP test in early disease and predict the development of erosive disease as well as extraarticular manifestations. We recently reported that many RA patients have anti-citrullinated albumin (ACA) ...
Cytokines are a broad class of tiny proteins that are essential for controlling inflammation and immunological responses. Numerous cell types, including fibroblasts, endothelial cells, immunological cells, and epithelial cells, produce these signaling molecules. Serving as intermediaries, they synchronize various cell functions to elicit the body's defense mechanisms against infections, tissue ...
In the vibrant realm of cellular biology and regenerative medicine, mesenchymal stem cells (MSCs) hold unparalleled potential for therapeutic applications. Particularly noteworthy are bone marrow mesenchymal stem cells (BM-MSCs), a subtype of MSCs. Their unique properties make them indispensable resources for developing ground-breaking solutions for various medical conditions. Mesenchymal stem ...
What is CD19 Understanding CD19: Definition and Role in the Immune System CD19, also known as Cluster of Differentiation 19, is a cell surface protein belonging to the immunoglobulin superfamily. It serves as a crucial marker for B cells, playing a pivotal role in the human immune system. While predominantly found on the surface of B cells, CD19 is rarely expressed on other immune cells. Its ...
Luminex multiplex assays is a multi-functional, multi-indicator parallel analysis system that organically integrates color-coded beads, laser technology, applied fluidics, the latest high-speed digital signal processor and computer algorithms to create a high degree of specificity and sensitivity for multi-factor detection. It can be widely used in immunoassay, nucleic acid research, enzymatic ...