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Biomaterials Articles & Analysis: Older
66 articles found
Idiopathic pulmonary fibrosis (IPF) is a devasting lung disease characterized by progressive scarring of lung tissue. As fibrosis develops, patients experience worsening shortness of breath, reduced lung capacity and ultimately respiratory failure. Current therapies for IPF rely on oral administration of pirfenidone and nintedanib, two FDA-approved drugs that slow disease progression. While ...
Chitosan is a natural, biodegradable polysaccharide derived primarily from the shells of shrimp, crabs, and fungi. Due to its biocompatibility, antimicrobial properties, and film-forming capabilities, chitosan is widely used in food preservation, water treatment, cosmetics, agriculture, and biomedical applications. 1. What is Chitosan? Chitosan is produced by the deacetylation of chitin, a ...
ByMatexcel
In surgical tissue recovery, focus is on controlling infection, managing inflammation, and ensuring wound closure. Beneath the surface—anatomically and biologically— the extracellular matrix (ECM) is undergoing remodeling ensure long-term tissue integrity. The ECM is a dynamic, biologically active network that orchestrates the entire process of tissue repair, remodeling, and ...
Watertown, MA – March 24, 2025 – Biopharma PEG, a leading supplier of high-quality polyethylene glycol (PEG) derivatives, highlights its innovative product DSPE-PEG-Mannose, an advanced biomedical polymer with significant potential in drug delivery, tumor-targeted therapy, tissue recognition, and adhesion.Structural Advantages of DSPE-PEG-MannoseDSPE-PEG-Mannose is composed of three key ...
The continuous advancement of biomaterials has led to the development of various copolymers, among which Poly(lactic-co-glycolic acid) (PLGA) and Polyethylene Glycol (PEG) copolymers have garnered significant attention. These materials are extensively utilized in drug delivery systems, tissue engineering, and regenerative medicine. This article presents a detailed comparison of PLGA and PEG ...
When it comes to the fascinating world of proteins, some names like collagen or hemoglobin might ring a bell. But what about tenascin-C, more commonly known as TNC protein? This often-overlooked molecule plays a vital, if subtle, role in how our cells talk to each other. Let's delve into the remarkable story of TNC protein and why it deserves more of the spotlight. What is TNC Protein? Before ...
Collagen is an important protein that is widely present in various human tissues, such as skin, bones, muscle tendons, and ligaments. Accurate determination of its concentration is crucial for multiple fields such as biomaterial research, food industry, and pharmaceutical research.Liquid Chromatography (LC) is an efficient and precise analytical technique for collagen concentration measurement, ...
The determination of collagen molecular weight is a technique used to determine the molecular weight of collagen, a complex protein. Collagen is one of the richest proteins in animals, mainly found in the skin, bones, tendons and connective tissue. Due to its key role in cell structure and tissue regeneration, accurate determination of the molecular weight of collagen is of great significance to ...
Dendrimers are highly branched polymers with a three-dimensional structure. They are characterized by expansive functional groups on their surface, which can be tailored to interact with specific molecules or to be used in a variety of applications. Dendrimers have attracted much attention in drug delivery, imaging, and materials science due to their unique structure, high monodispersity, and ...
The field of biomaterials is undergoing a transformative shift, driven by the integration of artificial intelligence (AI) technologies. As the demand for advanced materials with tailored properties continues to grow in applications ranging from tissue engineering to medical devices, researchers are increasingly turning to the power of AI to accelerate biomaterials development and optimization. ...
Imagine a world where diseases like cancer, Alzheimer's, and Parkinson's could be diagnosed and treated at the molecular level, long before symptoms even appear. This is the promise of fluorescent biopolymers, a revolutionary new class of materials that could transform the field of biomedical research. What Are Fluorescent Biopolymers? At their core, biopolymers are simply long chains of ...
ByMatexcel
In the intricate world of enzymes, one stands out for its remarkable ability to tackle some of the most resilient proteins found in nature - keratinase. This fascinating enzyme has captured the attention of scientists and industries alike, thanks to its unique capabilities and diverse applications. Keratin, a highly structured and durable protein, forms the backbone of many biological ...
Polymers play an important role in the biomedical field, and polyethylene glycol (PEG) and its derivatives are among the multifunctional polymers that have attracted much attention. PEG is a synthetic macromolecule with a linear structure consisting of glycol units (-CH2CH2O-) repeatedly linked. Its unique properties give PEG a wide range of applications. PEG is soluble in organic solvents and ...
Click chemistry has revolutionized the field of bioconjugation, offering a robust and versatile approach for linking biomolecules, such as proteins, peptides, nucleic acids, and carbohydrates, to create novel materials and probes. Traditionally, copper-catalyzed azide-alkyne cycloaddition (CuAAC) has been the cornerstone of click chemistry, but concerns about cytotoxicity and metal contamination ...
Proteins are the workhorses of life, performing a vast array of essential functions, from catalyzing biochemical reactions to building and maintaining cellular structures. Protein engineering, a rapidly evolving field at the intersection of biology, chemistry, and computer science, aims to harness the power of these molecular machines by designing and manipulating their structure and function to ...
Source of Marine Polysaccharides Marine polysaccharides are primarily sourced from a diverse range of marine organisms that thrive in oceans and seas. Seaweeds are the primary and most abundant source of marine polysaccharides. Seaweeds with high polysaccharide content, such as red algae (Rhodophyta), brown algae (Phaeophyceae), and green algae (Chlorophyta), have been extensively studied for ...
What is Hydrogel? Hydrogels are a class of widely studied and applied biomaterials. Hydrogels have been widely studied as cell scaffolds and drug delivery vehicles because their chemical and physical properties are very close to the natural environment of cells. Hydrogels can encapsulate both cells and biomolecules, and many gel systems can closely control the release properties through ...
The Use of Bioreactors In The Pharmaceutical IndustryThe pharmaceutical industry relies heavily on bioreactors to support a wide range of biological research applications, from cell therapy to vaccine development.1 These bioreactors provide a controlled environment for the growth of microorganisms, such as bacteria, cells, and algae, in order to produce biomolecules or biomaterials used in ...
Hydrogels are composed of hydrophilic polymers, whose three-dimensional network structure can not only absorb a large amount of water, but also be used to carry drugs. Hydrogels prepared with suitable materials have the characteristics of high biocompatibility, mechanical and viscoelastic control. Since the term was coined in the late 19th century, hydrogels have been widely used in drug ...
Another fantastic publication highlighting one of the multiple applications Atelerix products have within the scientific research and development industry. Anastassia Kostenko , Che J. Connon, and Stephen Swioklo (2023), have successfully shown that Atelerix BeadReady™ is a simple, adaptable solution for room temperature cell storage in combination with biofabrication and how this can be ...