Cancer Cell Targeting Articles & Analysis: Older
14 articles found
Bladder cancer, characterized by the uncontrolled proliferation of abnormal cells within the bladder lining, poses significant treatment challenges due to its potential to invade surrounding tissues and surrounding propensity for recurrence. The conventional therapeutic landscape has often fallen short in terms of specificity and effectiveness, necessitating a ...
Ensure Specificity and TargetingThe main advantage of ADC lies in its high specificity for specific cancer cell surface antigens. Biological activity analysis can verify whether ADC can accurately identify and bind to target antigens. This not only helps ensure therapeutic effects but also reduces non-specific damage to healthy ...
BOC Sciences offers a variety of linkers, including cleavable linkers, non-cleavable linkers, and pH-sensitive linkers, to accommodate different drug payloads and target antigens. These linkers are designed to be stable in circulation but release cytotoxicity upon internalization by target cancer cells, ensuring maximum ...
The antibody component specifically targets surface antigens on specific cancer cells, while the drug component is responsible for killing these bound cancer cells. ...
In the field of medicine, effectively delivering drugs to the target site in the body is crucial for successful treatment. Over the years, several innovative drug delivery systems have been developed to improve drug efficacy and patient outcomes. ...
In addition to causing degradation of the target protein HER2, SignalTAC also downregulates downstream signaling (PI3K/AKT/mTOR) and promotes apoptosis and inhibits the proliferation of HER2-driven cancer cells. ...
In the search for innovative and effective ways to target cancer, we are faced with more than just a challenging problem; we are faced with our own cells as opponents. ...
Gold nanocages can absorb light and heat, creating a photothermal effect that can kill cells. In fact, people use this effect to kill cancer cells. What are the differences between gold nanocages and nanorods? ...
Genetic mutations in cells are an important cause of cancer development, progression, and drug resistance. How to quickly and accurately translate massive tumor genomic information into safe and effective cancer targeted therapies in clinical practice is a scientific frontier today. ...
The researchers expose us to a radically different way of thinking in this article: instead of working on T cells, they focus on changing cancer cell antigens. They employed antibodies to deliver viral antigens to the tumor location and trigger virus-specific T lymphocytes to target cancer cells, ...
Novel cytotoxic drugs New cytotoxic drugs have been developed to target cancer cells with low antigen expression or resistance to auristatins or maytansinoids. ...
Gabrielle is researching novel α-helical peptide inhibitors of breast cancer oncogene LMO4. She has been working to redesign the peptide protein interface of LMO4 by replacing the traditional β-strand binding partners with novel inhibitory α-helical ones and designing a high throughput screening mechanism to identify these peptides. ...
In this study, we have designed a new protoporphyrin-conjugated gold nanoparticle to selectively target and photo- or sonodynamic therapy of tumoural cells. In order to improve the cell uptake effect of protoporphyrin and their derivatives, gold nanoparticle was chosen as carrier. ...