Capillary Electrophoresis Articles & Analysis: Older
6 articles found
Kits often come with instructions for validating the quality and quantity of the prepared libraries. Techniques such as capillary electrophoresis or high-throughput sequencing can be employed to assess library quality. ...
For instance, High-Performance Liquid Chromatography (HPLC) and Capillary Electrophoresis (CE) can be used to analyze the types and quantities of proteins and amino acids; Gas Chromatography (GC) and Mass Spectrometry (MS) can be used to analyze the composition of sugars and lipids; various biochemical analysis methods can be used to measure the content of growth ...
Variants like size-exclusion chromatography (SEC) help determine the molecular weight distribution, while reverse-phase HPLC (RP-HPLC) can separate and characterize conjugated and unconjugated species. Capillary Electrophoresis (CE) Capillary electrophoresis is another powerful tool for ADC characterization, offering ...
However, in the research and production process of peptide drugs, precise analysis must be performed to determine their purity, structure, charge, and other characteristics to ensure their efficacy and safety. Capillary Isoelectric Focusing (cIEF) analysis is an important peptide drug analysis technique.Capillary electrophoresis (CE), also known as ...
Current mass spectrometry techniques include liquid chromatography-mass spectrometry (LC-MS), gas chromatography-mass spectrometry (GC-MS), and capillary electrophoresis-mass spectrometry (CE-MS). LC-MS has the advantage of high sensitivity and high resolution and is capable of detecting more (200 to 500) metabolites. ...
Among these methods, middle-up and middle-down are more suitable for ADC analysis. Capillary Electrophoresis-Sodium Dodecyl Sulfate (CE-SDS) SDS is mainly used to separate ADCs with intact or H and L chain forms. ...