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Carcinoma Line Articles & Analysis: Older

2 articles found

Cancer Target: Mesothelin

Cancer Target: Mesothelin

In existing studies of human epidermoid carcinoma cell lines expressing mesothelin, biodistribution analysis of mesothelin using radiolabeled monoclonal antibodies showed good localization and specificity for relevant tumors. ...

ByCreative Diagnostics


Synthetic lethal kinases in Ras/p53 mutant squamous cell carcinoma

Synthetic lethal kinases in Ras/p53 mutant squamous cell carcinoma

To discover novel druggable targets for cancers carrying co-mutations in Ras and p53, we performed arrayed, kinome focused siRNA and oncology drug phenotypic screening utilizing a set of syngeneic Ras mutant squamous cell carcinoma (SCC) cell lines that also carried co-mutations in selected p53 pathway genes. These cell lines were derived from ...

BySEngine Precision Medicine

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