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Clinical Testing Articles & Analysis: Older

80 articles found

CCR1 Protein: A Chemokine Receptor at the Crossroads of Immunity and Disease

CCR1 Protein: A Chemokine Receptor at the Crossroads of Immunity and Disease

Blocking CCR1 can blunt harmful inflammation but risks impairing protective immunity. Clinical Relevance: From Autoimmunity to Oncology In autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, and inflammatory bowel disease, CCR1 signaling sustains leukocyte infiltration into tissues. ...

ByCreative BioMart


Adenovirus Production Services: A Comprehensive Overview

Adenovirus Production Services: A Comprehensive Overview

This step is crucial to ensure the safety and efficacy of the adenovirus for research and clinical applications. Quality Control: Rigorous testing is conducted to assess the purity, potency, and viral titer of the adenovirus. ...

ByCreative Biogene


Comprehensive Disease Models for Preclinical Drug Discovery

Comprehensive Disease Models for Preclinical Drug Discovery

It is the process that bridges the gap between basic research and clinical testing, allowing for the evaluation of potential drug candidates in biological systems before they are tested in humans. ...

ByCreative Biogene


Hydrogen and Methane Breath Testing in Children: A Practical Guide

Hydrogen and Methane Breath Testing in Children: A Practical Guide

Despite the seriousness of the need for HMBTs in children, the literature is extremely sparse for this age group, and testing clinics have to rely on the more robust adult consensus guidelines. ...

ByBedfont Scientific Limited


Understanding Colorectal Cancer Cell Lines: A Vital Tool in Cancer Research

Understanding Colorectal Cancer Cell Lines: A Vital Tool in Cancer Research

These cell lines serve as essential models for studying the biology of colorectal cancer, testing new therapies, and exploring the mechanisms of drug resistance. ...

ByCreative Bioarray


Mastering Gut Health: Key Insights from Our Webinar on SIBO and Carbohydrate Malabsorption with Melissa Dooley.

Mastering Gut Health: Key Insights from Our Webinar on SIBO and Carbohydrate Malabsorption with Melissa Dooley.

Melissa is a member of both the Irish Institute of Clinical Measurement Scientists and the British Society of Gastroenterology, as well as the founder and director of Gastrolife Clinic in Ireland. The webinar covers some important topics: · SIBO & dietary malabsorption · Finger-prick food intolerance testing. Does ...

ByBedfont Scientific Limited


Guidelines Spotlight: ESMO urge NGS testing for additional advanced cancers

Guidelines Spotlight: ESMO urge NGS testing for additional advanced cancers

ESMO updated its recommendations for NGS in advanced cancers this year, urging broader use of NGS in additional cancer types and the inclusion of tumor-agnostic biomarkers. The ESMO Precision Medicine Working Group (PMWG) first published its recommendations for when to use next-generation sequencing (NGS) in routine practice for patients with metastatic cancers in 20201. At that time, based ...

BySOPHiA Genetics


The NObreath® Utilising the Partition Method in FeNO Testing

The NObreath® Utilising the Partition Method in FeNO Testing

The NObreath® offers two test modes: A 12-second test mode and a 10-second test mode for those up to 10 years old who cannot complete the 12-second test mode. ...

ByBedfont Scientific Limited


Drug Antibody Testing

Drug Antibody Testing

Drug antibody testing is a laboratory testing method specifically designed to evaluate the immune response of the human body to certain drugs. ...

ByMtoZ Biolabs


Antibody Drug Activity Testing

Antibody Drug Activity Testing

To ensure the effectiveness and safety of these antibody drugs, it is necessary to perform activity testing.Definition of Antibody ActivityThe activity of an antibody drug usually refers to its ability to bind to the target antigen and how it affects the target in a biological function, such as neutralizing viruses, killing tumor cells, or regulating immune responses.Services at Mtoz Biolabs1. ...

ByMtoZ Biolabs


Small Molecule Drug Development at Alfa Cytology: Transforming Cancer Research

Small Molecule Drug Development at Alfa Cytology: Transforming Cancer Research

The process typically involves several stages, including target identification and validation, hit identification and lead optimization, preclinical testing, and clinical trials. Throughout the entire process, Alfa Cytology holds a strict quality system with various services covering AI-based drug design, hit-to-lead, drug screening, and lead optimization. ...

ByAlfa Cytology


FeNO Devices– Considerations when Investing

FeNO Devices– Considerations when Investing

Tests that are simple to perform are more likely to be used in primary care where time is short. ...

ByBedfont Scientific Limited


A Milestone in Global Health: A New Polio Vaccine Approved for Emergency Use

A Milestone in Global Health: A New Polio Vaccine Approved for Emergency Use

Years of research, collaboration, and testing have culminated in this achievement, promising new hope for a world free of polio. ...

ByB Medical Systems


Colored Polystyrene Particles in Developing Rapid and Affordable Point-of-Care Diagnostics

Colored Polystyrene Particles in Developing Rapid and Affordable Point-of-Care Diagnostics

POCT (Point-of-Care Testing) refers to clinical and bedside testing conducted in close proximity to patients. ...

ByCD Bioparticles


How to Apply In Vitro DMPK Services to Support Drug Development and ADMET Study

How to Apply In Vitro DMPK Services to Support Drug Development and ADMET Study

In vitro DMPK services, along with absorption, distribution, metabolism, excretion, and toxicity (ADMET) studies, play a vital role in predicting pharmacokinetic properties and potential adverse effects of drugs before they reach the clinical testing phase. In vitro DMPK services provide an array of tests that simulate the human body's response ...

ByCreative Bioarray


How to Apply In Vitro DMPK Services to Support Drug Development and ADMET Study

How to Apply In Vitro DMPK Services to Support Drug Development and ADMET Study

In vitro DMPK services, along with absorption, distribution, metabolism, excretion, and toxicity (ADMET) studies, play a vital role in predicting pharmacokinetic properties and potential adverse effects of drugs before they reach the clinical testing phase. In vitro DMPK services provide an array of tests that simulate the human body's response ...

ByCreative Bioarray


Gene Therapy for Cystic Fibrosis

Gene Therapy for Cystic Fibrosis

These treatments include antibiotics to treat lung infections, airway clearance techniques to clear mucus from the lungs, nutritional support, and medications that target specific mutations in the CFTR gene. Multiple clinical trials are currently underway to test new therapies for CF, including gene therapy and drugs targeting specific mutations in the CFTR ...

ByProtheragen


A new skin care peptide discovered

A new skin care peptide discovered

Using AI, Nuritas was able to identify the peptide and its activity, and successfully formulated it into various product matrices, demonstrating its efficacy on men’s and women’s skin in two clinical trials, compared to a placebo. According to Nuritas, PeptiYouth goes beyond the first generation of skincare peptides as we know them: a nature-identical peptide, it ...

ByNuritas Ltd.


Nuritas creates “world’s first” clinically tested anti-aging peptide discovered by AI

Nuritas creates “world’s first” clinically tested anti-aging peptide discovered by AI

The AI predicts peptides from in vitro to clinical efficacy with an 80% success rate. The development of an ingredient goes through three phases, from discovery to preclinical biology testing and clinical trials. ...

ByNuritas Ltd.


Unlocking nature’s secrets? How Nuritas harnesses AI to uncover hidden health-boosting ingredients

Unlocking nature’s secrets? How Nuritas harnesses AI to uncover hidden health-boosting ingredients

Through its bioactive peptide finder, Magnifier NπΦ, the company can boast a clinical trial success rate of 80%. Development of an ingredient goes through three phases, from discovery to preclinical biology testing and clinical trials. ...

ByNuritas Ltd.

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