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Dilute Samples Articles & Analysis: Older

2 articles found

Measurement of Elemental Impurities in a Higher Daily Dose Drug Product by USP <232>/<233> Using Ultrasonic Nebulization with ICP-AES Detection

Measurement of Elemental Impurities in a Higher Daily Dose Drug Product by USP <232>/<233> Using Ultrasonic Nebulization with ICP-AES Detection

The J value of the drug is calculated based on an established permissible daily exposure (PDE), maximum daily dose of the drug (MDD), and the dilution factor used in the sample preparation method. As a result of the J value calculation, drugs with a larger MDD require lower element impurity detection limits. An ultrasonic nebulizer (USN) is an accessory for ...

ByTeledyne CETAC Technologies


Development of an in vivo assay for detection of non-targeted radiation effects

Development of an in vivo assay for detection of non-targeted radiation effects

Patients undergoing radiotherapy treatment for cancer gave blood samples immediately after the first dose, midway during and six weeks after therapy. The serum from these samples was harvested, diluted in tissue culture medium and added to reporter cells. ...

ByInderscience Publishers

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