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Dna Target Articles & Analysis: This-Year
4 articles found
Understanding sgRNAs sgRNAs are short RNA sequences that guide the Cas9 protein to the target DNA. Typically, they consist of approximately twenty nucleotides complementary to the target DNA sequence, paired with a scaffold region that recognizes and binds to Cas9. ...
This system allows researchers to target specific DNA sequences within a genome, facilitating the addition, removal, or alteration of genetic information. ...
Researchers design guide RNA (gRNA) that directs the Cas9 nuclease to a specific genomic location. Once the target gene is located, Cas9 induces a double-strand break, leading to disruptions in the gene’s function. ...
Conventional therapies often fall short in their ability to selectively target cancer cells without impacting healthy tissues. Alfa Cytology’s small molecule PARPi development services are specifically designed to overcome these limitations by delivering bespoke, high-quality PARP inhibitors tailored to the unique molecular characteristics of various cancers. ...