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Alfa Cytology has announced its small molecule drug development to advance preclinical cancer research. Alfa Cytology, a comprehensive biotech company specializing in cancer research, has recently announced the cancer small molecule drug development services. The services tend to accelerate the discovery and optimization of molecule drugs with a strict quality control system. Small molecule drugs ...
The field of pharmaceuticals has seen rapid advancements in drug delivery technologies in recent years, one of which is long-lasting controlled-release microspheres technology. This technology involves the use of microscopic particles to deliver drugs in a controlled and sustained manner over an extended period of time. By encapsulating drugs within these microspheres, pharmaceutical companies ...
In order to more effectively deliver chemotherapy drugs, Small Molecule Drug Conjugates (SMDC), Antibody Drug Conjugates (ADC), and Degradation Antibody Conjugates (DAC) have been successively explored and developed, enhancing the therapeutic index while providing selective delivery. ...
Drug development is a complex and multifaceted process that involves extensive research and testing to ensure safety, efficacy and quality for human use. One critical element in the drug development process is drug metabolism and pharmacokinetics (DMPK), which refers to how a drug is absorbed, distributed, metabolized, and excreted (ADME) from the body. In vitro DMPK services, along with ...
In addition to traditional small molecule compounds, new types of payloads such as PROTACs and light-activated molecules have also been selected as payloads.New Strategies for ADC PayloadsADC with PROTAC Molecules as PayloadA major challenge in ADC development is dose-limiting toxicity (DLT), which demonstrates the difficulty in balancing the efficacy of drug ...
Drug development is a complex and multifaceted process that involves extensive research and testing to ensure safety, efficacy and quality for human use. One critical element in the drug development process is drug metabolism and pharmacokinetics (DMPK), which refers to how a drug is absorbed, distributed, metabolized, and excreted (ADME) from the body. In vitro DMPK services, along with ...
Microspheres play a crucial role in the field of pharmaceuticals, biotechnology, and materials science due to their unique properties and applications. These spherical particles, ranging from a few micrometers to several millimeters in size, have a wide range of uses, including drug delivery systems, cell encapsulation, and as supports for various chemical reactions. Polymeric microspheres, ...
The various applications of animal models in drug development and highlights their significance in advancing medical discoveries: Understanding Disease Pathways: Animal models enable researchers to mimic the complex biological processes underlying various diseases, allowing for a deeper understanding of the mechanisms involved. ...
Atrial Fibrillation (AF) is often described as an irregularly irregular rhythm. AF is an arrhythmia with no consistent ventricular response or pattern due to its somewhat random and chaotic discharging of atrial impulses firing disconnectedly from multiple foci. This continuous and erratic behavior results in a ventricular response that changes from beat to beat. AF will typically present with a ...
Abstract: On January 1, 2018 the U.S. Pharmacopeia (USP) enacted new criteria for element impurities in finished drug products. These criteria, detailed in USP/, recommend analysis of drug products for element impurities by either ICP-AES or ICP-MS. Laboratories must measure impurities based on a J value for each drug product; drug products may be oral, parenteral (ex. intravenous, injection), or ...
The research summarized in this whitepaper provides a number of examples of how ALZET® pumps offer a superior pre-clinical drug dosing option for the delivery of a wide array of anti-cancer agents, including small molecules, immunotherapies, radiotherapies, combination treatments, and novel drug entities. This whitepaper also explores how ALZET® pumps have been used to successfully test ...
Poorly managed healthcare can be directly attributed to extensive drug regimens. Numerous chronic illnesses and epidemics such as HIV/AIDS and tuberculosis require elaborate drug regimens for efficacious therapeutic outcomes. Various drug delivery systems have been developed to simplify their regimental drug therapy. However, more effective and innovative drug delivery technologies are required ...
Customer: GE Healthcare Challenge: Increasing patient safety in surgery and intensive care through more accurate monitoring. Solution: Development of measurement parameters for the adequacy of anesthesia and analgesia. Key benefits: More precise monitoring of the level of anesthesia and analgesia. Preventing excess medication which can damage the patient's vital functions. Cost-efficiency ...