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Drug Release Delivery Articles & Analysis: Older
174 articles found
In the fast-evolving field of antibody–drug conjugates (ADCs), linker chemistry plays a decisive role in defining therapeutic performance. The ability to control the drug-to-antibody ratio (DAR), conjugation site, and overall molecular stability directly impacts both efficacy and safety. Among emerging linker materials, azide-functionalized PEG derivatives have become essential tools for ...
Precise and safe delivery of drugs to target sites has always been an important task for researchers in modern medicine. ...
Chitosan is a natural, biodegradable polysaccharide derived primarily from the shells of shrimp, crabs, and fungi. Due to its biocompatibility, antimicrobial properties, and film-forming capabilities, chitosan is widely used in food preservation, water treatment, cosmetics, agriculture, and biomedical applications. 1. What is Chitosan? Chitosan is produced by the deacetylation of chitin, a ...
ByMatexcel
Virus-like particles (VLPs) have garnered significant attention in recent years for their potential applications in vaccine development, drug delivery, and as tools in various biotechnological fields. These nanoparticles mimic the structure of viruses but lack the viral genetic material that makes viruses infectious. This unique characteristic offers a versatile platform for various innovative ...
Lipid synthesis is an integral process within biochemistry that contributes to a myriad of biological functions, including energy storage, cell membrane formation, and signaling pathways. As researchers delve deeper into the complexities of lipid biology, the demand for precise and efficient lipid synthesis techniques has become increasingly evident. This article explores the various methods ...
Whether it is medical research or drug manufacturing, tablet press is a vital link. Let's see how to choose the one that suits you best.Grand pack.The field of drug delivery is constantly evolving, driven by the core goal of improving therapeutic outcomes—enhancing efficacy, reducing toxicity, boosting patient compliance, and even enabling entirely new medical treatments. The global drug delivery ...
Introduction PEGylation, the process of attaching polyethylene glycol (PEG) chains to therapeutic molecules, has become a cornerstone in pharmaceutical development. This technique improves the pharmacokinetic and pharmacodynamic properties of drugs, enhancing their stability, solubility, and circulation time while reducing immunogenicity. Since its first FDA-approved application in 1990 with ...
In our last blog, Peter discussed how AI is accelerating the drug discovery process and putting pressure on chemists, who must find ways of developing these potential drugs for subsequent testing or production. ...
ByBUCHI
The unique properties of platelets including easy acquisition and strong targeting capabilities together with convenient release options and long circulation times make them ideal drug delivery carriers with weak cytotoxicity and high biosafety which enables their development into effective drug delivery systems. ...
The MDCK permeability assay is a critical technique employed in pharmacology and drug development to evaluate the permeability of drug candidates across epithelial cell layers. This assay utilizes Madin-Darby Canine Kidney (MDCK) cells, which are a widely used model for studying intestinal absorption and permeability due to their similarity to human epithelial cells. Importance of the MDCK ...
Single-domain antibodies, also known as nanobodies or VHH antibodies, are a unique class of antibody fragments derived from the immune systems of camelids, such as llamas and alpacas. These small yet robust molecules present significant advantages in various applications, from therapeutics to diagnostics. This article explores the process of single-domain antibody production, its benefits, and ...
It is used in dressings and other wound care products. l Drug Delivery: Researchers are exploring the use of bioglass as a drug delivery system. Its porous structure allows it to be loaded with drugs, which can then be released slowly over time as the bioglass degrades. ...
ByMatexcel
Hydroxyapatite (HA), a naturally occurring mineral form of calcium apatite, has emerged as a cornerstone material in modern science and technology. Its unique properties, such as biocompatibility, bioactivity, and structural similarity to human bone and teeth, make it indispensable in fields like biomedical engineering, environmental science, and advanced materials. This article delves into the ...
ByMatexcel
Watertown, MA – March 24, 2025 – Biopharma PEG, a leading supplier of high-quality polyethylene glycol (PEG) derivatives, highlights its innovative product DSPE-PEG-Mannose, an advanced biomedical polymer with significant potential in drug delivery, tumor-targeted therapy, tissue recognition, and adhesion.Structural Advantages of DSPE-PEG-MannoseDSPE-PEG-Mannose is composed of three key ...
As the new year begins, many people prioritize their health by scheduling annual physicals and medical check-ups. While these routine exams ensure overall well-being, few realize the crucial role that fluoropolymers play in modern medical technology. From diagnostic tools to life-saving devices, fluoropolymer materials contribute significantly to patient safety, hygiene, and the accuracy of ...
These materials are extensively utilized in drug delivery systems, tissue engineering, and regenerative medicine. ...
The evolution of 3D printing technology has opened up new avenues in the pharmaceutical industry, especially in the fabrication of novel drug delivery systems. One such advancement is the 3D printing of Oral Thin Films (OTFs), which are ultra-thin films used to deliver drugs via oral mucosa. Unlike traditional methods, 3D printing allows the ...
In the healthcare industry, plastics’ role is more profound than what the average person sees every day. Plastics maintain sterility with packaging and gloves, enable precise drug delivery through syringes, and are critical in life- saving equipment like heart valves and dialysis machines. Devices and components such as these often tip the scales in life threatening situations and can directly ...
In addition, exosomes themselves are being investigated as drug delivery vehicles due to their ability to carry specific biomolecules. By manipulating the lipid and metabolic content of exosomes, researchers aim to enhance the specificity and efficacy of drug delivery systems. Another exciting area of research is the potential ...
In the field of medical device manufacturing, the materials used in creating life-saving equipment must meet the highest standards of safety, reliability, and performance. Among these materials, fluoropolymer tubing has emerged as a critical component, playing a crucial role in various medical devices. Whether it’s for intravenous (IV) systems, catheters, or diagnostic equipment, ...