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Flow Cell Articles & Analysis: Older
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Introduction to Variant Analysis Rare DNA changes within a population of cells are the first manifestations of mutations, which are the fuel for evolution. ...
The binding of folate molecules on the nanoparticle surface to folate receptors on cell surfaces allowed for more efficient cellular uptake of the drug, further increasing drug uptake within cells. Cell penetration experiments using flow cytometry confirmed the cell-selective uptake properties of the ...
• Surface Attachment and Bridge Amplification The reaction of Solexa sequencing is carried out in a glass tube called flow cell, and flow cell is subdivided into 8 Lanes, each of which has a number of fixed single strand joints on the inner surface of each Lane. ...
Spacing between posts, along with a brief electric field, allows for T cells to flow through without significant physical deformation or perturbation of the cell state. The vortices created by the posts apply hydrodynamic forces to the cell membrane which cause temporary pores allowing for the diffusion and electrophoretic ...
Ryan Pawell is the founder and CEO of Indee Labs, a Berkeley biotech. The mission of Indee Labs is to use microfluidic vortex shedding as a scalable method to deliver CRISPR reagents into cells for developing affordable cell and gene therapies in the future. In our previous blog post, we summarized the work from their latest publication on CRISPR-editing in T cells using microfluidic devices. In ...
One technique that provides measurable benefits for the parenteral drug industry is flow microscopy. The technique is applicable for both subvisible and visible particles. The principle of operation of this technology is to integrate the functions of microscopy, digital imaging, fluidics and image analysis to automatically enumerate and characterize (in terms of size, shape and ...