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Genetic Mutation Articles & Analysis: This-Year
4 articles found
The choice of therapy typically hinges on the tumor’s receptor status and specific genetic mutations. For instance, hormone receptor-positive tumors may benefit from endocrine therapy, while HER2-positive cancers might be treated with targeted agents like trastuzumab. ...
First, it enables researchers and clinicians to detect specific genetic alterations that may influence the behavior of the tumor. For instance, identifying mutations in genes such as ERBB2 (involved in cell growth and differentiation) through FISH can help determine appropriate targeted therapies for breast cancer patients. ...
Various factors contribute to this phenomenon, including genetic mutations, alterations in drug targets, enhanced drug efflux, and changes in metabolic pathways. ...
The most commonly used colorectal cancer cell lines include HCT116, SW480, and HT-29, each with distinct genetic and phenotypic characteristics. Applications in Research Colorectal cancer cell lines are instrumental in various research applications. ...