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Genomic Analysis Articles & Analysis: Older
38 articles found
The formation of embryoid bodies, which contain cells representing multiple lineages, and the subsequent assessment of specific lineage markers provides insights into the differentiation potential of the iPSCs. Genomic Integrity Maintaining genomic integrity is crucial for the safety of iPSCs, especially for therapeutic applications. ...
Comparative genomic analyses reveal that commercially available L. acidophilus powders differ markedly in key functional elements: Bacteriocin production genomics: Strains such as L. acidophilus NCFM contain complete operons for lactacin B production, while others (e.g., La-14) exhibit truncated bacteriocin genes, resulting in differential antimicrobial ...
Fosmid libraries represent a pivotal advancement in the field of genomics and molecular biology, offering a robust method for genomic cloning and analysis. ...
Degradome sequencing, also known as parallel analysis of RNA ends (PARE) sequencing, is a cutting-edge technique that leverages high-throughput sequencing and bioinformatics to investigate the degradation products of mRNA. ...
Next-Generation Sequencing (NGS) has revolutionized genomics, providing unprecedented insights into the structure and function of genomes, transcriptomes, and epigenomes. ...
In addition to raw sequence data, you can also submit computationally assembled sequences, genomes, functional genomics data, microarray data, clinical data, genome variations, and other data types, such as PacBio methylation data. ...
The detailed point is to sequence the unknown genome sequence, and use bioinformatics analysis means to splice and assemble the sequence, so as to obtain the map of its genome. For coverage, the genome sequence assembled after sequencing analysis usually cannot completely cover all regions due to the existence ...
Using early data from differential proteomics/transcriptomics/genomics analysis, this method has validated biomarkers in large biological sample sizes. ...
Applications and Advantages of Variant Analysis The following areas can benefit from variant detection analysis on whole-genome resequencing or reduced representation genome sequencing: (1) molecular markers, (2) pathogenic gene, (3) molecular breeding, (4) mining trait genes, (5) evolution, and (6) genetic polymorphism database. ...
Oxford Nanopore Technologies (ONT) sequencing has witnessed significant progress in recent years, becoming a key player in the genomics field. As the technology matures, so does the bioinformatics analysis of ONT data. ...
Expert Team: CD Genomics boasts an experienced research team capable of tailoring experimental designs and data analysis to specific research objectives. Comprehensive Data Analysis: In addition to delivering raw data, CD Genomics offers a suite of data analysis services, including mRNA quantification, ...
With the development of genomic technology, researchers have found that a single reference genome can no longer meet the needs of genomic data analysis, and more and more species, including the human genome, are choosing to construct a pan-genome instead of a single reference ...
However, with recent advancements in technology, specifically in the realm of genomics, whole genome sequencing (WGS) has emerged as a powerful tool that has revolutionized the diagnosis and management of rare diseases. ...
(2) Evaluation of viral vector purity: detect and quantify impurities derived from the host cell system where the vector product is produced or from downstream purification processes using sensitive and ready-to-use methods. (3) Capsid analysis of viral vectors: capsid analysis of viral vectors, including purity analysis, full/empty capsid ...
Amplicon sequencing is a cutting-edge technique that involves sequencing PCR products or captured fragments of specific lengths, enabling the analysis of sequence variations. Among the diverse applications of this technology, the 16S rRNA gene has emerged as a fundamental tool for sequence-based bacterial analysis, boasting decades of significance. ...
By predicting and annotating all genes in the genome, they aim to identify genes associated with various phenotypes, including drug resistance, heavy metal resistance, and environmental adaptability. ...
Small RNA sequencing, an example of targeted sequencing, is a powerful method for small RNA species profiling and functional genomic analysis. Here, we present the guidelines for bioinformatics analysis of small RNA sequencing. ...
Finally, CD Genomics provides detailed analysis reports that help researchers gain an in-depth understanding of T-cell clone diversity and clonality in the samples. ...
WGS can be used for variant calling, genome annotation, phylogenetic analysis, reference genome construction, and more. ...
They are generally divided into fungi, actinomycetes, bacteria, spirulina, rickettsia, chlamydia, mycoplasma and viruses. Microbial whole genome sequencing is an important tool for mapping genomes of novel organisms, finishing genomes of known organisms, or comparing genomes across multiple samples. Sequencing the entire ...