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Hiv Virus Articles & Analysis: Older

14 articles found

Frontiers in Antiviral Research 2024

Frontiers in Antiviral Research 2024

Such advancements could lead to potent treatments for chronic viral infections such as hepatitis C and HIV, which have long evaded complete eradication. Immunomodulatory Therapies The concept of harnessing the body’s immune response against viral infections has gained traction over the years. ...

ByBOC Sciences


Understanding the Workflow and Practical Applications of Drug Affinity Responsive Target Stability (DARTS)

Understanding the Workflow and Practical Applications of Drug Affinity Responsive Target Stability (DARTS)

Gong et al. also demonstrated that DCA can lead to abnormal aggregation of reactive oxygen species (ROS) through histone D (CTSD) and thioredoxin-like protein 1 (TXNL1), and that Akt-mTOR, the most important negative regulatory pathway for autophagy, is inhibited. 3. Identification of the anti-HIV targets of ratjadone A Fleta-Soriano et al. found that Ratjadone A, a ...

ByCreative Proteomics


Nano-Flow Cytometry: A Revolutionary Tool for Biomedical Research

Nano-Flow Cytometry: A Revolutionary Tool for Biomedical Research

Cancer, Alzheimer's disease, and Parkinson's disease are just a few of the illnesses for which EVs can be used as biomarkers. Viruses: Viruses like HIV and SARS-CoV-2 can be detected and quantified using nano-flow cytometry. ...

ByCreative Biostructure


Host Cell Residual DNA: Understanding its Significance and Detection Methods

Host Cell Residual DNA: Understanding its Significance and Detection Methods

For instance, rcDNA may carry the HIV virus or the Ras oncogene. The insertion of LINE-1 sequences, found in mammalian cell genomes, into chromosomes as retrotransposons can impact the functionality of essential genes, potentially activating oncogenes or inhibiting tumor suppressor genes. ...

ByCreative Proteomics


New Methods Can Be Appled for iPSC Differentiation

New Methods Can Be Appled for iPSC Differentiation

Thus, the inclusion of specific sequences from the Human Immunodeficiency Virus Transactivator of Transcription (HIV-TAT), including the TAT protein, allows pluripotency-inducing factors (OCT4, SOX2, c-MYC and KLF4) to reach the nucleus and target key promoters area. ...

ByCreative Bioarray


Understanding the Structure of the HIV Protein May Lead to New Treatments

Understanding the Structure of the HIV Protein May Lead to New Treatments

Scientists from Rutgers University and Salk Institute have determined the molecular structure of HIV Pol polyprotein, which plays a key role in helping the virus spread itself and systemically. ...

ByCreative Biostructure


Needlestick Injury - the pointy end of a preventable pandemic

Needlestick Injury - the pointy end of a preventable pandemic

The re-use of injection equipment is responsible worldwide for 32% of new HBV infections, 40% of new HCV infections, and 5% of all new HIV infections[3]. These needlestick injury and infection statistics are frightening, result in billions of dollars spent on related health care, and are largely preventable if the use of safe medical devices designed to reduce this risk of these ...

ByNumedico Technologies Pty Ltd


World Immunization Week: Taming Latent Viruses for Longer Lives

World Immunization Week: Taming Latent Viruses for Longer Lives

Such viruses are called “latent,” and include Epstein-Barr virus (EBV), Varicella-Zoster virus (VZV), HIV, Herpesviruses, and Cytomegalovirus (CMV). ...

ByModerna, Inc.


The 3rd AIDS patient is "cured"! Has mankind finally conquered AIDS?   

The 3rd AIDS patient is "cured"! Has mankind finally conquered AIDS?  

At an academic conference on Feb 15, U.S. experts announced the world's first female AIDS "cure," making it the third case of HIV infection to be cured. After therapy and withdrawal of antiviral drugs, HIVs were not identified in the patient's body for more than 14 months, indicating that the virus was in complete remission, according to ...

ByCreative Biolabs


Water, sanitation and hygiene practice and associated factors among HIV infected people in Arba Minch town, Southern Ethiopia

Water, sanitation and hygiene practice and associated factors among HIV infected people in Arba Minch town, Southern Ethiopia

Human immunodeficiency virus (HIV) infected people have substantially greater need for water, sanitation and hygiene (WASH). Many opportunistic infections cause high morbidity and mortality in people living with HIV (PLHIV) than in immune competent populations. The objective of the study was to assess WASH practices and associated factors ...

ByIWA Publishing


Risky (legal) business: HIV and criminal culpability in Victoria

Risky (legal) business: HIV and criminal culpability in Victoria

This article examines HIV transmission jurisprudence in the Australian state of Victoria. It details the development of criminal legislation to respond to the issue of HIV and the application of these offences to prosecute charges of HIV transmission in Victoria. ...

ByInderscience Publishers


Rationalising fixed dose combinations for tuberculosis and acquired immunodeficiency syndrome therapy

Rationalising fixed dose combinations for tuberculosis and acquired immunodeficiency syndrome therapy

Numerous chronic illnesses and epidemics such as HIV/AIDS and tuberculosis require elaborate drug regimens for efficacious therapeutic outcomes. ...

ByInderscience Publishers


Engineering of a human vaginal lactobacillus strain for surface expression of two-domain cd4 molecules

Engineering of a human vaginal lactobacillus strain for surface expression of two-domain cd4 molecules

Women are at significant risk of heterosexually transmitted human immunodeficiency virus (HIV) infection, with the mucosal epithelium of the cervix and vagina serving as a major portal of entry. The cervicovaginal mucosa naturally harbors dynamic microflora composed predominantly of lactobacilli, which may be genetically modified to serve as a more efficient ...

ByAmerican Society for Microbiology (ASM)


Preclinical and safety studies of V-1 Immunitor

Preclinical and safety studies of V-1 Immunitor

Liver and kidney and other biochemical and blood parameters remained normal. In Phase I study about 9% of HIV-positive patients reported mild adverse reactions which did not last more than one week. ...

ByInderscience Publishers

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