Immune Therapy Articles & Analysis: Older
17 articles found
The rat thymus, an essential organ in the immune system, plays a crucial role in the development and maturation of T-cells. ...
Cancer treatment has witnessed transformative advancements over the past few decades, notably with the emergence of CAR-T (Chimeric Antigen Receptor T-cell) therapy. This revolutionary therapy harnesses the body's immune system by genetically engineering T-cells to target and destroy cancer cells. ...
Alfa Cytology employs state-of-the-art techniques including isolation, culture, engineering, expansion, and characterization of immune cells and stem cells to develop novel cell therapies. These innovative solutions are grounded in a comprehensive understanding of tumor biology and immune system dynamics, empowering researchers to accelerate ...
Such advancements could lead to potent treatments for chronic viral infections such as hepatitis C and HIV, which have long evaded complete eradication. Immunomodulatory Therapies The concept of harnessing the body’s immune response against viral infections has gained traction over the years. Immunomodulatory therapies aim to enhance the ...
Cell therapy constitutes a form of treatment where live cells are induced into a patient's body to effectuate reconstruction or repair of damaged tissue or to enhance the body's immune system. ...
Through peptide sequencing, we can discover new peptide drugs with specific bioactivity, such as peptide hormones and peptide antibodies, providing powerful tools for targeted therapy. At present, peptide drugs have shown broad application prospects in the treatment of tumors, hepatitis, diabetes, and AIDS.Antibody-Based TherapyAntibodies are proteins produced by the ...
Dr. Kate Sasser from Tempus led a discussion on the potential of antibody-drug conjugates (ADCs), their challenges in targeting tumor antigens, and the future of cancer treatment with Dr. Daniel Johnson, Dr. Funda Meric-Bernstam, and Dr. Kellogg Parsons. The oncology field is rapidly advancing with the development of antibody-drug conjugates (ADCs), offering new hope for ...
ByTempus
There are unlimited uses for point mutation cell lines at pre-defined loci, including functional assays, drug screening, FACS screening of membrane proteins, gene expression studies, gene therapy and antibody immunization boosting research. The RNA-guided DNA endonuclease Cas9 associates with a synthetic single guide RNA (gRNA) and cleaves double-stranded DNA ...
It is often used in synergistic photodynamic therapy and chemotherapy and immune enhancement therapy for hypoxic tumors. ...
Cell therapy constitutes a form of treatment where live cells are induced into a patient's body to effectuate reconstruction or repair of damaged tissue or to enhance the body's immune system. ...
Its primary function revolves around converting extracellular ATP into immunosuppressive adenosine, working in tandem with CD39 within normal tissues to curtail excessive immune reactions. However, this mechanism is often hijacked by tumors, utilizing CD73 to foster an adenosinergic process that shields them from immune assaults. ...
The combination of an IL-6 blocker with an immune checkpoint inhibitor reduced experimental autoimmune encephalomyelitis (EAE) symptoms and improved tumor control, suggesting that the combination suppresses inflammatory responses and may enhance antitumor immunity. To validate the findings, the researchers retrospectively analyzed 31 melanoma patients who ...
Background Tumor immunotherapies compose immune checkpoint inhibitors, therapeutic antibodies, tumor vaccines, cellular therapies, and so on. However, each has its own set of issues, such as the fact that CAR-T therapy is an individual therapy that is costly; immune checkpoint inhibitors are highly effective, ...
There are various therapeutic approaches involving TACA, including vaccine-induced active immunity, as well as genetically engineered development of monoclonal antibodies. ...
Near-infrared photoimmunotherapy (NIR-PIT) is a molecularly targeted light therapy for cancer. The therapy is mainly composed of monoclonal antibodies (mAb) directed against the antigen expressed on the surface of cancer cells and a near-infrared light-absorbing dye (IR700) that has cell-killing properties. Traditional immunotherapies, such as ...
A key hurdle to making adeno-associated virus (AAV) capsid mediated gene therapy broadly beneficial to all patients is overcoming pre-existing and therapy-induced immune responses to these vectors. ...
How autoantibody profiling can further unlock the success of CPI therapy Immunotherapy has revolutionised the treatment of cancers, improving the prognosis for a variety of malignancies. ...