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Integrated Diagnostics For Early Detection Articles & Analysis: Older
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The world of drug development has long been marked by the rigorous assessment of cardiac safety. Recognizing the need for a more accurate and efficient evaluation system, the Comprehensive in vitro Proarrhythmia Assay (CiPA) initiative emerged. At the heart of this initiative are CiPA Translational Assays, designed to improve the prediction of drug-induced cardiac arrhythmias. Understanding the ...
In the evolving landscape of healthcare technology, mobile ECG devices have emerged as a transformative tool for monitoring heart health. While traditional ECG machines have been pivotal in diagnosing and managing cardiovascular conditions, mobile ECG devices offer distinct advantages that make them a compelling choice for modern healthcare. Here’s a look at the key benefits of mobile ECG ...
ByPanonIT
In many rural and underserved regions, advanced healthcare services are often limited due to factors like a shortage of specialists, long travel distances, and scarce resources. However, technological advancements, especially in mobile health devices, are beginning to bridge these gaps. Mobile ECG (electrocardiogram) devices are at the forefront of this transformation, revolutionizing cardiac ...
ByPanonIT
Medical ventilators are significant medical devices, using positive pressure to circulate air through the lungs of patients who cannot breathe effectively on their own. Modern ventilators integrate a variety of sensors that can automatically adapt to changes in lung function or breathing, minimizing required input from medical personnel. Cubic offers a comprehensive range of gas sensing solutions ...
The purpose of an anesthesia machine is to deliver precise amounts of anesthetic gases or medications to patients during surgical procedures to maintain anesthesia. Throughout this process, closely monitoring key respiratory parameters, including EtCO2 (end-tidal carbon dioxide concentration) and oxygen levels, could ensure the patient's respiratory function remains normal and safe. Given that ...
Drug development is a complex and multifaceted process that involves extensive research and testing to ensure safety, efficacy and quality for human use. One critical element in the drug development process is drug metabolism and pharmacokinetics (DMPK), which refers to how a drug is absorbed, distributed, metabolized, and excreted (ADME) from the body. In vitro DMPK services, along with ...
Introduction Microneedles have gained significant attention in recent years due to their potential applications in various fields such as drug delivery, diagnostics, and tissue engineering. The preparation of microneedles requires precise and efficient technologies to achieve desired features such as size, shape, and mechanical strength. This article provides an overview of different ...
Drug development is a complex and multifaceted process that involves extensive research and testing to ensure safety, efficacy and quality for human use. One critical element in the drug development process is drug metabolism and pharmacokinetics (DMPK), which refers to how a drug is absorbed, distributed, metabolized, and excreted (ADME) from the body. In vitro DMPK services, along with ...
In the realm of modern medicine, the quest for new and effective drugs to combat various diseases is a continuous journey. Drug discovery, the process of identifying compounds that can potentially treat diseases, has seen a significant transformation in recent years, thanks to advancements in computational biology and artificial intelligence (AI). In this article, we will delve into the ...
Why need viral vector characterization? Cell and gene therapies for various rare diseases are currently undergoing clinical trials worldwide. The rapid development in this field has led to an increase in regulatory scrutiny and product characterization requirements, as well as a bottleneck in viral vector supply. The manufacturing processes and analytical tools for gene therapy viral vectors need ...
Case Study Description Warming Waters and Metabolic Rates As climate change continues to warm our world and its waters, scientists and researchers across the globe have spent years attempting to understand and predict the ramifications such warming will have on Earth’s ecosystems. Predictions can range from mild effects to the catastrophic, but one team of researchers are finding that a ...
My previous post, Pathway Analysis vs Gene Set Analysis, ended with an interesting question: has anybody really compared side-by-side gene set analysis methods and pathway analysis methods on the same data sets? Well, the answer is: not yet! The main reason for this is that it is extremely difficult to objectively validate the results of a pathway analysis method. It is even more difficult to ...
The research goals of Carole Ober’s laboratory at the University of Chicago are to identify genetic variants that influence gene expression and epigenetic patterns in tissues relevant to complex phenotypes, especially related to asthma and fertility. The lab uses both freshly isolated cells, as well as tissue and cell culture models of gene-environment interactions to explore ...
People living with frontotemporal dementia, or FTD, are commonly misdiagnosed with psychiatric disorders or Alzheimer’s disease and other causes of dementia, such as Parkinson’s disease and vascular dementia. While frontotemporal dementia and Alzheimer’s disease can both cause dementia, there are distinct differences in impacted regions of the brain and, consequently, ...
The day a person receives a cancer diagnosis is likely one of the worst days of their lives. For some new patients, the typical approach may be to seek care from a specialist at an NCCN-designated cancer center. But for the majority of Americans, it will be a community oncologist who guides them through their cancer journey. That’s why Adaptive recently partnered as a sponsor with ...
SmartTab is pioneering a wireless remote controlled drug delivery system, has completed pre-clinical animal studies and is preparing for human clinical trials for its core technology TargetTab™. This proprietary and patented wireless capsule will revolutionize targeted drug delivery and medicine adherence. DENVER, CO — Prescription pills are often delivered to the wrong site, at ...
BySmartTab
Meditation is often thought of as an avenue to clarity and self-awareness, but it may also be an avenue to better brain health. Emerging research suggests meditation may have significant benefits to brain health, ranging from improved mental and behavioral health to enhanced cognitive function. In this article, we will break down how meditation helps the brain and provide helpful tips for ...
Many neurological diseases, including Alzheimer’s disease, can be thought of as continuums, whether the presence and manifestation of the disease are different depending on the stage of the disease. In this article, we provide a high-level overview of the stages in the Alzheimer's disease continuum, with a focus on preclinical Alzheimer’s disease and its importance in patient care and ...
In addition to the pandemic, the digitization of healthcare is rapidly shifting clinical trials from analog to hybrid or fully decentralized clinical trials, catalyzing the development and implementation of digital health technologies to support clinical research. Digital endpoints not only support the decentralization of clinical trials but also provide a means to collect more sensitive, ...
Alzheimer’s and Parkinson’s disease are both neurological diseases that cause progressive damage to the brain, resulting in a decline in neurocognitive function. While Parkinson’s disease is known for affecting movement and function and Alzheimer’s disease is known for affecting cognition, they are a bit more complex than that. Below, we provide an overview of ...