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Ion Exchange Articles & Analysis: Older
7 articles found
Protein A affinity chromatography is widely used for monoclonal antibody capture, but due to its high cost, researchers are investigating alternatives such as mixed-mode resins, synthetic ligands, and membrane-based affinity systems. Beyond capture, ion-exchange, hydrophobic interaction, and size-exclusion chromatography remain vital polishing steps to ensure ...
Techniques such as affinity chromatography, size exclusion chromatography, and ion-exchange chromatography are typically employed to achieve high-purity products. ...
Ion chromatography (IC) is an analytical technique used to separate and quantify ionic and polar analytes. IC has become widely accepted by the pharma industry and regulatory bodies for an expanded range of applications like water quality and chemical analysis. It has qualified in recent years to analyze pharmaceuticals. The United States Pharmacopeia-National Formulary (USP-NF, US Pharmacopeia ...
ByB&W Tek
The disadvantages are low selectivity and limited sample loading. 2. Ion exchange chromatography Ion exchange chromatography is an adsorption chromatography that separates molecules based on the charge difference. ...
The disadvantages are low selectivity and limited sample loading. 2. Ion exchange chromatography Ion exchange chromatography is an adsorption chromatography that separates molecules based on the charge difference. ...
The sample is homogenized with a generic extraction solution and the crude soluble portion is directly injected into an HPLC ion-exchange column. The column effluent is then mixed with an OPA/Thiofluor reagent which forms highly fluorescent derivatives with the primary amine moieties of the antibiotics. ...
Betweeninjection time is 13 min while actual time is only 7 min. The Pickering lithium ion-exchange column has a matched set of eluant and regenerant to provide the best possible separation, sensitivity, and reproducibility. ...