Ipsc Articles & Analysis: Older
16 articles found
The PC vaccine development services at Alfa Cytology are more targeted & feasible and ensure excellent functions in extensive research, including whole-cancer cell vaccine development, iPSC-based vaccine development, dendritic cell-based vaccine development, and so on. ...
The process of iPSC differentiation to neurons and neuronal cells is of special importance for neurobiology and related disorders, considering the dearth of clinically relevant in vitro models available for research, drug screening and development, as well as the lack of therapy to reverse neuronal damage. Benefits and advantages of iPSC differentiation to ...
A key concern in iPSC-based therapeutic applications is the safety of the cell products to be transplanted into patients. ...
This article will take an in-depth look into the process of iPSC differentiation and the integral role iPSC differentiation kits play in accelerating biological research. iPSC differentiation is a crucial step in harnessing the potential of these remarkably versatile cells. ...
For those who are not familiar with the matrix, it is comprised of truncated recombinant Laminin-511 protein and is designed to support the health and pluripotency of induced pluripotent stem cells (iPSCs). Unlike most iPSC matrices, MatriClone is optically suited for whole well imaging required for regulatory approval and is soluble, meaning that pre-coating of ...
Previously, it was thought that glial cells, which support neuronal activity, metabolize most of the glucose in the brain. However, by using induced pluripotent stem cells, the researchers found that neurons were able to take up glucose and process it into smaller metabolites. In mice, normal function of neurons depends on glycolysis. The findings could help develop new treatments for ...
The clinical presentation of COVID-19-related illness ranges from asymptomatic to mild respiratory symptoms resembling influenza infection to acute symptoms including pneumonia requiring hospitalization and admission to the intensive care unit. COVID-19 starts in the upper airways and lungs, but in severe cases can also affect the heart, blood vessels, brain, liver, kidneys, and intestines. ...
Polyarginine-fused pluripotency-inducing factors can also efficiently enter cells and induce iPSCs. Collectively, the discovery of these four key transcription factors continues to drive the development of new strategies focused on the use of iPSCs in regenerative and personalized medicine. ...
The iPSC’s capacity to yield large numbers of pluripotent cells able to differentiate into almost any somatic cell type is attractive. ...
Many cell and gene therapy solutions have shown considerable promise as a source of possible treatments for a wide range of chronic disorders. However, these sophisticated therapies introduce additional barriers such as the requirements for ultra-low and cryogenic storage, which affect numerous steps of the biomedical solutions’ life cycles, from their development to their administration. ...
We had the chance to interview Teisha Rowland, Ph.D., Principal Scientist at Umoja Biopharma during the ISSCR in San Francisco about the Umoja/TreeFrog partnership. Leading iPSC engineering at Umoja, she comes back on the vision of Umoja, its RACR™ technology and her interest in TreeFrog’s C-Stem™ platform for the development of iPSC-derived ...
Mark explains how pioneering work conducted in the 1980’s sparked the development of opti-ox, and when this uniquely engineered genetic switch is applied to cell reprogramming it enables the deterministic induction of a new cell identity from human iPSCs, into any cell type on a vast scale. opti-ox forms the basis of bit.bio’s ioCells and within this interview he goes ...
Bybit.bio
Co-founder Ryan Bethencourt is one of the investors behind Sustainable Food Ventures Cultivated Meat Startups Landscape: Enabling Technologies Here’s the full list in alphabetical order: Agulos Biotech (US, 2017, cell culture media) — developing Simulated Platelet Lysate (porcine), a replacement for FBS Back of the Yards Algae Sciences (US, 2018, cell culture media) — algae ...
This is the third module in a four part series titled “Zero to One on the basic science behind cultivated meat”. You can click on these links to access: Course Overview, Module 1 (Cell Culture Basics), Module 2 (Cell Sources), Module 4 (Process monitoring). Learning objectives By the end of this module, you should understand: Basal culture medium composition and sources; ...
However, with new stem cell technologies, it is now possible to use primary human stem cells and induced pluripotent stem cells (iPSCs) to create cell lines and tissues in the lab. iPSCs are a cutting-edge technology with a wide range of applications, but they have drawbacks in achieving a physiologically accurate intestinal model. ...
Collectively, these results suggest that bioprinted kidney organoids are functionally equivalent to those prepared manually and thus are likely to be useful for toxicity screening, the development of iPSC-based approaches for the interrogation of complex disease phenotypes, and the scaling needed for clinical restoration of renal function with patient-derived ...