Lung Support Articles & Analysis: Older
5 articles found
Cystic fibrosis (CF) is a rare genetic disorder that affects the lungs, digestive system, and other organs. It is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which encodes a protein that regulates chloride ions transport across cell membranes. ...
Supplementation of mesothelin or MPF to stimulate the growth of MSLN knockout mice promotes lung cancer growth, which supports the role of mesothelin in tumor cell adhesion, migration and metastasis. The Role of Mesothelin in Cancer Mesothelin is expressed in many solid tumors, most commonly in mesothelioma, epithelial ovarian and pancreatic cancers, but also in ...
A study conducted under the Lung Cancer Master Protocol (Lung-MAP) found that when treated with a combination of ramuzumab (Cyramza) and Keytruda, Patients with advanced NSCLC whose cancer progressed during prior immunotherapy lived significantly longer than when treated with one of the current standard therapies for this cancer. ...
Serum samples collected on 0,4, and 7 DPI and lung samples collected on 7 DPI were tested by PRRSV RT-qPCR. Formalin-fixed lung samples were subject to histopathology and immunohistochemistry (IHC) examinations. ...
Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal lung disease. A maladaptive epithelium due to chronic injury is a prominent feature and contributor to pathogenic cellular communication in IPF. Recent data highlight the concept of a “reprogrammed” lung epithelium as critical in the development of lung fibrosis. Extracellular ...