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Metabolic Resistance Articles & Analysis: Older

4 articles found

Preclinical Models of Non-Alcoholic Fatty Liver Disease

Preclinical Models of Non-Alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease (NAFLD) has emerged as a significant public health concern, associated with obesity, insulin resistance, and a spectrum of metabolic disorders. Understanding this condition is crucial for effective intervention and treatment. ...

ByCreative Bioarray


In Silico Development of Combinatorial Therapeutic Approaches Targeting Key Signaling Pathways in Metabolic Syndrome

In Silico Development of Combinatorial Therapeutic Approaches Targeting Key Signaling Pathways in Metabolic Syndrome

Methods Targets were chosen based on the clustered clinical risks in metabolic syndrome: dyslipidemia, insulin resistance, impaired glucose control, and chronic inflammation. ...

ByVeriSIM Life


Multiplex real-time PCR: A guide to application

Multiplex real-time PCR: A guide to application

Multiplex real-time PCR: A guide to application In multiplex real-time PCR (qPCR), scientists amplify two or more target genes in the same reaction, using the same reagent mix. Multiplexing allows scientists to overcome limitations for myriad applications. First and foremost, multiplexing enables scientists to conserve valuable samples used in a quantitative assay, which is especially ...

ByAnalytik Jena - an EndressHauser Company


Impact of luxs and suppressor mutations on the gastrointestinal transit of lactobacillus rhamnosus GG

Impact of luxs and suppressor mutations on the gastrointestinal transit of lactobacillus rhamnosus GG

The LuxS enzyme, catalyzing the production of the autoinducer-2 signaling molecule, also forms an integral part of the activated methyl cycle and the metabolism of methionine and cysteine. The genuine luxS mutant CMPG5412 showed drastically reduced persistence in mice, which was related to less survival in simulated gastric juice, indicating that LuxS metabolism ...

ByAmerican Society for Microbiology (ASM)

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