Model Atl04 Liver Articles & Analysis: Older
2 articles found
The liver plays an incredibly important role in the human body by metabolizing drugs and other compounds. Developing accurate in vitro liver models to study is a critical step in better understanding the biological dynamics of our bodies and removing our dependence on animal models. In their recent publication, Allevi authors Marie Cuvellier, Frédéric Ezan, Hugo Oliveira, Sophie ...
Publication Summary: Compound induced chronic liver injury can lead to initiation of profibrotic processes resulting in sustained production of growth factors and profibrotic cytokines where inflammation, tissue remodeling and repair pathways are activated simultaneously to counteract the injury. Evaluation of potential antifibrotic therapies are limited using conventional non-human animal ...