Pathology Disease Articles & Analysis: Older
16 articles found
Glycan Profiling in Disease Diagnosis Glycan microarrays are increasingly being used for glycan profiling in disease diagnosis, particularly in cancer and infectious diseases. ...
These therapies have radically revamped disease treatment modalities, transcending traditional approaches to become some of the most groundbreaking advancements in modern healthcare. ...
Upon administration, liposomes can protect encapsulated drugs from degradation, prolong their circulation time, and facilitate targeted delivery to diseased tissues via passive or active targeting mechanisms. Passive targeting exploits the enhanced permeation and retention (EPR) effect, a phenomenon observed in certain pathological tissues, such as tumors, ...
The measurement of collagen can help researchers and physicians understand the pathological process of related diseases (such as osteoporosis, arthritis, skin aging etc.), and also aid in drug development and other biomedical research.The measurement of collagen can usually be carried out through several different methods:Mass Spectrometry1. ...
Autophagy has also been implicated in pathological conditions including neurodegenerative diseases, cancer, and inflammatory diseases. Modulation of autophagy has become a potential therapeutic target in human diseases. To monitoring and measuring autophagy, it is necessary to label and visualize the phagophores and ...
These post-translational modifications are not only vital for cell function, but their abnormal changes are also associated with cancer, neurodegenerative diseases, and other pathological conditions. Therefore, research on histone PTMs can help to deepen our understanding of disease mechanisms and develop new therapeutic strategies. ...
Rare diseases are characterized by their low prevalence, affecting a small number of people across the world. ...
Dysregulation of Cytokine Signaling Dysregulation of cytokine signaling can lead to a wide range of pathological conditions, including autoimmune diseases, inflammatory disorders, and cancer. ...
These therapies have radically revamped disease treatment modalities, transcending traditional approaches to become some of the most groundbreaking advancements in modern healthcare. ...
The field of medical science has long utilized disease models, which are systems simulating the progression and expression of a disease, to better understand various illnesses. These models facilitate the study of disease pathology, identifying underlying mechanisms, and developing potential treatments. In the context of ...
The field of medical science has long utilized disease models, which are systems simulating the progression and expression of a disease, to better understand various illnesses. These models facilitate the study of disease pathology, identifying underlying mechanisms, and developing potential treatments. In the context of ...
Cytokine Dysregulation in Systemic Immune Diseases The perturbation of immune tolerance leads to disruption in cytokine homeostasis. ...
Many neurological diseases, including Alzheimer’s disease, can be thought of as continuums, whether the presence and manifestation of the disease are different depending on the stage of the disease. In this article, we provide a high-level overview of the stages in the Alzheimer's disease continuum, with a focus on preclinical Alzheimer’s disease and its importance in patient care and ...
Intestinal inflammatory diseases are highly complex, which has thus far prevented development of an effective in vitro disease model. ...
Here, PPI-FIT was tested for the first time on the cellular prion protein (PrP), a cell surface glycoprotein playing a key role in fatal and transmissible neurodegenerative pathologies known as prion diseases. We predicted the all-atom structure of an intermediate appearing along the folding pathway of PrP and identified four different small molecule ligands for ...
General clinical characteristics of 25 dead patients: all of them have basic diseases, including 16 cases of hypertension, 10 cases of diabetes, 8 cases of heart disease, 5 cases of kidney disease, 4 cases of cerebral infarction, 2 cases of chronic obstructive pulmonary disease, 2 cases of malignant tumor, 1 case of acute ...