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Pharmaceuticals Articles & Analysis: This-Year
39 articles found
Location: Al-Hayat Pharmaceutical Manufacturing Company, Jeddah, Saudi Arabia Background: Al-Hayat Pharmaceutical is an old manufacturing facility that was built in 1972. This company produces the following range of products: Antibiotics: (syrup & tablet) including Ciprofloxacin (broad-spectrum) Clindamycin (gram-positive) Ampicillin (broad spectrum) Anti-diarrheal product (syrup) a ...
Fluoropolymers: A Critical Enabler in Cell and Gene Therapies Cell and gene therapies are revolutionizing medicine, offering cures for rare diseases and innovative treatments for cancer. Behind every successful therapy is a precise and sterile manufacturing process—where the choice of materials can make the difference between success and ...
Hey everyone in the kidney community—whether you're battling IgA nephropathy (IgAN) yourself, supporting a loved one, or just here to learn—let's talk about something that's got me genuinely excited. For years, living with IgAN felt like a waiting game: watching your kidneys slowly decline, relying on blood pressure meds, and hoping dialysis or a transplant wasn't around the corner. ...
For a vaccine manufacturer contracted to fast-track production of COVID-19 vaccines, we designed and constructed a 700-square-foot Ultra-Low Temp storage ...
In today’s highly regulated industrial landscape, ensuring SIL2 compliance in additive manufacturing and pharmaceutical production is critical. These sectors rely on accurate, safe, and compliant equipment to maintain operations and protect both employees and end-users. One standard that has emerged as a benchmark in safety-critical processes is SIL2 compliance. This article explores what ...
The rat thymus, an essential organ in the immune system, plays a crucial role in the development and maturation of T-cells. Investigating the thymus of rats provides valuable insights into immunological processes and disease mechanisms. One of the most effective methods for preserving and studying the cellular architecture of the rat thymus is through the use of Formalin-Fixed Paraffin-Embedded ...
Many oncology drugs have been abandoned by pharmaceutical companies due to poor performance in phase I, II, or III clinical trials. These drugs represent untapped potential treatments for indications outside of those initially investigated. With research and development costs for a single new drug estimated between $2–3 billion, abandoned drugs represent an opportunity to bring drugs to ...
When you hear the word "sterol," your mind probably jumps to one famous, and often misunderstood, molecule: cholesterol. We’re constantly bombarded with messages about "good" and "bad" cholesterol, and its impact on our cardiovascular health. But what if I told you that cholesterol is just one member of a vast and vital family of molecules called sterol lipids? This diverse group is ...
Abstract In pharmaceutical synthesis, heavy metal catalysts are commonly used, and their residues often remain in the final product. These heavy metals—primarily from catalyst residues—not only affect drug efficacy but also pose serious health risks to patients. As a result, pharmacopoeias in various countries impose strict limits on heavy metal content in pharmaceutical substances. ...
Lipid synthesis is an integral process within biochemistry that contributes to a myriad of biological functions, including energy storage, cell membrane formation, and signaling pathways. As researchers delve deeper into the complexities of lipid biology, the demand for precise and efficient lipid synthesis techniques has become increasingly evident. This article explores the various methods ...
In the pharmaceutical industry, excipients play a crucial role in the formulation of medicines. These inactive substances, which are combined with the active pharmaceutical ingredient (API), perform various functions that enhance the effectiveness, stability, and overall performance of drug products. Understanding the common types of excipients is essential for pharmaceutical scientists and ...
As seasonal allergies affect millions globally, the demand for advanced, reliable treatments is growing rapidly. Behind the scenes of this progress lies a powerful class of materials: fluoropolymers. While often associated with aerospace, semiconductor, and chemical industries, fluoropolymers also play a vital—yet underappreciated—role in pharmaceutical manufacturing, particularly in ...
In the ever-evolving field of biopharmaceuticals, the production of antibodies has taken center stage due to their critical role in therapeutic applications. Among the various production systems available, Chinese Hamster Ovary (CHO) cells have emerged as a gold standard for monoclonal antibody production, and specialized services have been developed to streamline this process. The Significance ...
Recombinant protein expression is a cornerstone of modern biopharmaceutical development, providing the means to produce proteins with therapeutic potential, enzymes, and antibodies. Among various expression systems, Chinese Hamster Ovary (CHO) cells have emerged as the preferred choice for many researchers and pharmaceutical companies. This article delves into the significance of recombinant ...
Whether it is medical research or drug manufacturing, tablet press is a vital link. Let's see how to choose the one that suits you best.Grand pack.The field of drug delivery is constantly evolving, driven by the core goal of improving therapeutic outcomes—enhancing efficacy, reducing toxicity, boosting patient compliance, and even enabling entirely new medical treatments. The global drug delivery ...
Introduction PEGylation, the process of attaching polyethylene glycol (PEG) chains to therapeutic molecules, has become a cornerstone in pharmaceutical development. This technique improves the pharmacokinetic and pharmacodynamic properties of drugs, enhancing their stability, solubility, and circulation time while reducing immunogenicity. Since its first FDA-approved application in 1990 with ...
The increasing application of Lactobacillus species in biotechnology, pharmaceutical sciences, and clinical research has necessitated a more nuanced understanding of strain-specific characteristics and formulation parameters. This is particularly relevant for researchers working with lactobacillus acidophilus powder and selecting appropriate lactobacillus strains for specialized applications. ...
Active Pharmaceutical Ingredients (APIs) form the foundation of modern pharmaceuticals, serving as the biologically active components responsible for the therapeutic effects of medications. These crucial compounds undergo rigorous research, development, and manufacturing processes before being integrated into final pharmaceutical formulations. The pharmaceutical landscape encompasses a diverse ...
Alfa Cytology has revealed new FAP-targeted therapeutics development services that aim to develop precise and effective cancer treatments. Alfa Cytology has introduced its groundbreaking initiative which targets fibroblast activation protein(FAP) for cancer therapies. These solutions focusing on FAP to improve treatment accuracy and deliver customized projects that strive to obtain more ...
In the realm of pharmacology and drug development, the assessment of drug permeability is essential. One of the most widely recognized in vitro models for evaluating the intestinal absorption of compounds is the Caco-2 permeability assay. This assay plays a pivotal role in understanding how drugs are absorbed in the gastrointestinal tract and aids in predicting their bioavailability. Background ...