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Physiological Environment Articles & Analysis: Older

8 articles found

3D Co-culture Models

3D Co-culture Models

Cell cultures have played a significant role in the academy and pharmaceutical industry, but conventional 2D cultures fail to provide physiological relevance and communication network as compared to in vivo conditions, since they are unable to mimic the complexity of cellular microenvironment, an essential part for the cell behavior and systematic investigation. ...

ByCreative Bioarray


How to Design a Good ADC Drug

How to Design a Good ADC Drug

Most ADCs are characterized by a cleavable linker, which releases cytotoxins through reduction, acidity, or proteolysis of the linker according to the physiological environment of the cell. On the other hand, for ADCs with non-cleavable linkers, the antibody would need to be degradedly completely after ADC internalization for the payload to be released. l Lysine ...

ByBOC Sciences


Do You Really Know Hydroxyapatite?

Do You Really Know Hydroxyapatite?

According to the chemical activity in the physiological environment, bioceramics can be divided into three types: Nearly inert bioceramics, only weak or no chemical reaction occurs when exposed to the physiological environment for a long time, and can maintain long-term stability; Surface-active bioceramics, can form chemical ...

ByMatexcel


Introduction to Microbiomics

Introduction to Microbiomics

The microbiome refers to the collection of all microorganisms and their genetic information in a specific environment or ecosystem, and its connotation includes the interaction of microorganisms with their environment and host. Microbiomics is the study of the microbiome, which explores their structure, function, and relationship with the ...

ByCreative Proteomics


Introduction to Microbiomics

Introduction to Microbiomics

The microbiome refers to the collection of all microorganisms and their genetic information in a specific environment or ecosystem, and its connotation includes the interaction of microorganisms with their environment and host. Microbiomics is the study of the microbiome, which explores their structure, function, and relationship with the ...

ByCreative Proteomics


Physiological and cellular responses of oysters (Crassostrea hongkongensis) in a multimetal‐contaminated estuary

Physiological and cellular responses of oysters (Crassostrea hongkongensis) in a multimetal‐contaminated estuary

In the present study, a euryhaline oyster, Crassostrea hongkongensis, was collected from different sites of the Pearl River estuary; and various physiological (heart rate, alkaline phosphatase as homeostatic regulation, and glycogen as energy reserve) and cytological (lysosomal membrane stability) biomarkers were quantified to assess this species as a potential bioindicator of ...

ByJohn Wiley & Sons, Ltd.


Synthesis of biphasic calcium phosphate powders by a simple hydrolysis process

Synthesis of biphasic calcium phosphate powders by a simple hydrolysis process

An ideal bone grafting material should be compatible with physiological environment, provoke osseous tissue formation and adapt degradation behaviour to new bone tissue growth. ...

ByInderscience Publishers


In vitro exposure to fullerene C60 influences redox state and lipid peroxidation in brain and gills from Cyprinus carpio (Cyprinidae)

In vitro exposure to fullerene C60 influences redox state and lipid peroxidation in brain and gills from Cyprinus carpio (Cyprinidae)

Studies concerning the impact of nanomaterials, especially fullerene (C60), in fresh water environments and their effects on the physiology of aquatic organisms are still scarce and conflicting. ...

ByJohn Wiley & Sons, Ltd.

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