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Prostate Tumors Articles & Analysis: Older
51 articles found
Anti-Tumor APIs: Pioneering Cancer Treatment Anti-tumor Active Pharmaceutical Ingredients (APIs) are vital in today's medical landscape, addressing one of the most pressing health challenges: cancer. These APIs form the foundation of various therapeutic strategies aimed at inhibiting or destroying tumor cells in the human body. The classification ...
In the environment of cancer, antigens may be specific to tumor cells and are known as tumor-specific antigens (TSAs) or tumor-associated antigens (TAAs). ...
ESMO updated its recommendations for NGS in advanced cancers this year, urging broader use of NGS in additional cancer types and the inclusion of tumor-agnostic biomarkers. The ESMO Precision Medicine Working Group (PMWG) first published its recommendations for when to use next-generation sequencing (NGS) in routine practice for patients with metastatic cancers in 20201. At ...
In addition, Trop-2 is highly expressed in tumors and is associated with poor tumor prognosis. These characteristics all indicate that Trop-2 will become a good target for tumor treatment. ...
The FDA's Center for Drug Evaluation and Research (CDER) regulatory approval of a total of 26 NME (New Molecular Entity) drugs in the first half of 2023. It is worth noting that the 26 drugs approved include 4 peptide drugs, accounting for 15% of the total. In the past 2022, the FDA has approved only three peptide drugs: Tirzepatide, Lutetium 177Lu Vipivotide Tetraxetan and Terlipressin, of which ...
B7-H3 is expressed in limited amounts in normal tissues but is highly expressed in various cancers, including prostate cancer cells. It is involved in the formation and development of the tumor microenvironment (TME) and plays an important role in regulating immune responses. ...
Enzymes are protein molecules that catalyze chemical reactions in living organisms. They are involved in many metabolic processes and play a critical role in maintaining the health of the body. In recent years, enzymes have been widely used in disease diagnosis, providing a quick and accurate way to detect and monitor diseases. Enzymes for disease diagnosis can be divided into two categories: ...
Targeted protein degradation (TPD) is a promising strategy in the field of drug discovery. In recent years, targeted protein degradation (TPD) technology has developed rapidly, especially proteolysis targeting chimera (PROTAC), which is the most representative technology of TPD strategy. TPD drugs are one of the hot spots of new drug development in recent years, especially in the field of ...
For example, the enzyme lactate dehydrogenase (LDH) is often used as a marker for cancer progression, as increased levels of LDH in the blood can indicate tumor growth. Another enzyme, prostate-specific antigen (PSA), is commonly used to diagnose and monitor prostate cancer. ...
X-ZELL is collaborating with Singapore General Hospital (SGH) and the National University Hospital Singapore (NUH) to explore how X-ZELL single-cell diagnostics may aid in the early detection of clinically significant prostate cancer in whole blood. The prospectively blinded, 400-patient multi-centre study officially commenced in 2020 and will lay the foundation for the launch of a commercially ...
The literature shows that pathologists, being only humans under considerable pressure, may miss cancer in up to 1-3% of prostate biopsies.2,3,4 Considering the over one million men who are diagnosed worldwide per year, this may reflect a large number of patients.5 Moreover, the subjectivity of Gleason grading and tumor quantification can result in difficulty ...
By comparing the toxicity of chitosan oligosaccharides with different molecular weights and different degrees of deacetylation to prostate cancer cells PC3, lung cancer cells A549 and liver cancer cells HepG2, the researchers found that chitosan with low molecular weight and low degree of deacetylation has Better anti-tumor effect. ...
It was also observed in a study that while the photothermal macromolecular delivery enhancements were similar for the two systems when dosed by optical density, the tumoral uptake and biodistribution profiles for each of these shapes differed, with the nanocages residing in the liver, kidneys and spleen for less time than the nanorods. ...
Currently, ADC has played a significant role in the treatment of some malignant tumors, such as trastuzumab in the treatment of breast cancer, but its application in the treatment of prostate cancer (PCa) progress slowly. ...
LFQ is frequently used to search tumor biomarkers in clinical studies, as tumor adjacent or normal tissues are often treated as control group. de Oliveira et al. found that MMP-7 was presented as a more promising biomarker associated with useful assays of clinical practice for gastric adenocarcinoma patient diagnosis via LFQ results. ...
There are a ton of practical uses for computer vision at present times. One industry where this technology is increasingly useful in healthcare. It is impossible to exaggerate the value of computer vision services in the medical field. Its methods continue to be used more widely since they have demonstrated excellent utility in numerous medical contexts, including surgical planning and medical ...
Movember is an annual initiative where men from around the globe grow mustaches to raise awareness for men’s health causes, including mental health and suicide prevention, testicular cancer, and prostate cancer. Through events, fundraising, and using mustaches as a light-hearted starting point for important conversations, the movement supports men in taking charge of their health to live ...
You may have heard of Movember, the month when men grow their facial hair in solidarity with men’s health issues, like testicular and prostate cancer. The trend has taken hold across the world and even generated its own spinoffs, like “No-Shave November.” Movember started in Australia as a grassroots movement and began to become widespread in the early 2000s. Since then, ...
Background Since Walsh and Donker first introduced the anatomic nerve-sparing technique for retropubic radical prostatectomy1 (RRP) in the treatment of clinically localized prostate cancer, the importance of minimizing damage to the neurovascular bundle (NVB) has been recognized as a critical element for the preservation of potency and urinary continence post-prostatectomy. Although originally ...
Yale Medicine, an academic medical center with a high volume of prostate biopsies, conducted a study to determine Paige Prostate’s utility as a prescreening tool for clinical use. A total of 1,876 prostate core biopsy slides were analyzed by Paige Prostate, and only those cores categorized by the AI as “suspicious” or as out of distribution were manually reviewed by Yale ...