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Pulmonary Inflammation Articles & Analysis: Older

3 articles found

ELANE Protein: A Dual-Edged Regulator of Inflammation, Immunity, and Tissue Remodeling

ELANE Protein: A Dual-Edged Regulator of Inflammation, Immunity, and Tissue Remodeling

However, the same proteolytic activity that protects against pathogens can, when unregulated, contribute to tissue injury, autoimmune inflammation, and chronic disease progression. In recent years, recombinant ELANE protein has become an indispensable tool for researchers studying neutrophil function, protease regulation, and disease mechanisms, particularly in ...

ByCreative BioMart


The Potential of WNT/B-Catenin Modulation in Treating Pulmonary Fibrosis

The Potential of WNT/B-Catenin Modulation in Treating Pulmonary Fibrosis

Pulmonary fibrosis, particularly idiopathic pulmonary fibrosis (IPF), represents a significant challenge in healthcare due to its detrimental impact on lung function and limited treatment options. While WNT/β-catenin signaling plays a crucial role in lung development and maintenance of adult lung stem cells, its dysregulation has been associated with pulmonary fibrosis. However, recent ...

BySCIREQ - an emka TECHNOLOGIES Company


Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine

Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine

Here, we show that compared with smoke exposure, mice receiving ENDS vapor for 4 months failed to develop pulmonary inflammation or emphysema. However, ENDS exposure, independent of nicotine, altered lung lipid homeostasis in alveolar macrophages and epithelial cells. ...

ByJohnson Controls, Inc.

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