Therapeutic Value Articles & Analysis: Older
8 articles found
While upstream cell culture or fermentation focuses on producing the target biomolecule, downstream steps transform crude harvests into highly purified and stable therapeutic products. For biologics such as monoclonal antibodies, recombinant proteins, and viral vectors, downstream processing can account for the majority of production costs, making process optimization both a ...
However, due to their large size and low lipophile characteristics, they cannot effectively cross the cell membrane, so the application of these biomacromolecules with therapeutic value in medical fields is greatly limited. Currently, the commonly used methods for introducing biological macromolecules into cells include liposome mediated method, virus vector ...
Learn more by watching “Real Talk, Fresh Takes: How Sage Therapeutics is Unleashing the Operational Value of Real-Time Dosing ...
ByAiCure
"In the past, scientists have tested molecules one by one against therapeutic targets, a long and expensive operation," Roth said. Therefore, scientists have constructed virtual molecular libraries and complex computer programs to test hundreds of thousands of molecules at a time. ...
Therefore, the treatment of DLBCL also needs to find more new therapeutic targets. Liposomal prostaglandin D synthase (L-PGDS), also known as PTGDS, is located on human chromosome 9 (9q34.2 to 34.3), a region of the lipocalin family. ...
“This has tremendous potential therapeutic value,” said Douglas Brenneman, chief pharmacologist at Neuropathix leading the development of KLS-13019. ...
Auris's technology, called the Monarch Platform, received FDA approval for use in diagnostic and therapeutic bronchoscopy in 2018. Pitchbook valued Auris at $2.2 billion following its most recent Series D1 funding round in November. ...
The authors coupled fish plasma modeling of therapeutic hazard values with field monitoring of water chemistry variability and pharmaceutical occurrence to examine whether therapeutic hazards to fish existed within these urban coastal ecosystems and whether therapeutic hazards differed within and among coastal locations and ...