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Vascular Inflammation Articles & Analysis: Older

5 articles found

Matrix Metalloproteinases (MMPs) - Structure, Sources and Functions

Matrix Metalloproteinases (MMPs) - Structure, Sources and Functions

MMPs are secreted by pro-inflammatory cells and uteroplacental cells, including fibroblasts, osteoblasts, endothelial cells, vascular smooth muscle, macrophages, neutrophils, lymphocytes, and cytotrophoblasts. ...

ByCreative Proteomics


Inflammatory Cytokines Profile

Inflammatory Cytokines Profile

Interleukin-17 (IL-17) IL-17 is an important soluble factor in the process of T-cell induction and promotion of inflammation. It promotes neutrophil development and maturation and stimulates the production of inflammatory transmitters such as IL-6, IL-8, granulocyte colony-stimulating factor and prostaglandin E2 (PGE2) by epithelial cells, endothelial cells, macrophages and ...

ByCreative Proteomics


Exploring Knowledge Graphs for COVID-19 Drug Discovery

Exploring Knowledge Graphs for COVID-19 Drug Discovery

Today, there are only a few therapies approved to treat COVID-19, but while novel therapies can take decades and billions of dollars to develop, are there opportunities to repurpose existing drugs for new therapies? Our latest whitepaper showcases how CAS Knowledge Graphs reveal new connections and insights that identify drugs to potentially repurpose. Drug repurposing is critical for faster ...

ByChemical Abstracts Service (CAS)


How One Smart MedTech Company is Leveraging Innovation to Save the Lives and Limbs of VTE Patients

How One Smart MedTech Company is Leveraging Innovation to Save the Lives and Limbs of VTE Patients

Riyaz Bashir, Professor of Medicine and Director of Vascular and Endovascular Medicine at Temple University Hospital. Dr. ...

ByThrombolex, Inc.


Integrin α5β1 regulates PP2A complex assembly through PDE4D in atherosclerosis

Integrin α5β1 regulates PP2A complex assembly through PDE4D in atherosclerosis

Abstract Fibronectin in the vascular wall promotes inflammatory activation of the endothelium during vascular remodeling and atherosclerosis. ...

ByJohnson Controls, Inc.

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