Virus Vectors Articles & Analysis: Older
9 articles found
For biologics such as monoclonal antibodies, recombinant proteins, and viral vectors, downstream processing can account for the majority of production costs, making process optimization both a scientific challenge and a commercial necessity. ...
Oncolytic Viruses are wrought using an array of techniques, each technique contingent on the virus strain and the cancer form it targets. It is essential to curate a virus capable of adeptly identifying and effacing cancer cells. Among the pantheon of techniques are 'transduction' and 'transfection', both circumscribing the introduction of foreign DNA to ...
Currently, the commonly used methods for introducing biological macromolecules into cells include liposome mediated method, virus vector mediated method, electroporation method and microinjection method, etc. ...
One approach to integrative gene therapy is to use viral vectors, such as retroviruses, adenovirus (Ad), adeno-associated viruses (AAV), and helper-dependent adenoviruses (Hd-Ad), to deliver the corrected CFTR gene. ...
The main types of viral vectors used clinically for in vivo gene therapy include adenovirus, adeno-associated virus (AAV), herpes simplex virus (HSV), retroviruses, and lentiviruses. ...
Advances in molecular technology have facilitated the development of other platforms, such as recombinant protein vaccines, nucleic acid vaccines, and viral vector vaccines, which have further diversified global vaccine development. ...
Early in January 2020, sequencing revealed a novel coronavirus (now termed SARS-CoV-2) as the causal factor for the disease designated as COVID-19. The pandemic caused by the virus has unforeseen effects on the global economy and modern society, leading to a global race to find a suitable treatment and a preventive vaccine. ...
ByNuvonis
In addition, viral vectors based on Newcastle disease virus have been previously evaluated as vaccines against e.g. Sars-CoV-2, Ebola, H5N1 influenza, West Nile, and Simian Immunodeficiency virus. Also, oncolytic Newcastle disease viruses and vectors are seen as a promising immunotherapeutic strategy against various cancers. ...
ByNuvonis
Gene therapy vectors are intended to deliver therapeutic genes without making copies of themselves. Whereas other vectors require careful engineering to handicap their ability to replicate in vivo, with AAV we get this property automatically. ...