Neutron capture therapy at the MEPhI reactor

Nov. 15, 2004- By: K.N. Zaitsev; A.A. Portnov; O.V. Mishcherina; V.N. Kulakov; V.F. Khokhlov; I.N. Sheino; V.V. Meshcherikova; V.N. Mitin; N.G. Kozlovskaya; I.A. Shikunova;

Courtesy ofInderscience Publishers

The article discusses the results of the creation and development of the irradiation base for Neutron Capture Therapy (NCT) at the MEPhI Reactor, development and studies of boron- and gadolinium-containing compounds, and presents the results of pre-clinical NCT studies in large laboratory animals – dogs with spontaneous melanoma.

Keywords: nuclear reactors, neutron capture therapy, melanoma, boron compounds, gadolinium compounds, irradiation base, dogs, cancer, malignant tumors