Affimed GmbH
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Affimed GmbH products

Science and Technology

Affimed - Redirected Optimized Cell Killing Platform

The proprietary ROCK platform enables a tumor-targeted approach that can be tailored across hematological and solid tumors. The ROCK (Redirected Optimized Cell Killing) platform allows for a modular approach to generating customizable ICE (innate cell engager) molecules. High-affinity ICE (innate cell engager) molecules, which are created using the ROCK platform, are capable of bivalent NK-cell binding via CD16A without inducing nonspecific NK-cell activation or cell fratricide.