Ascendia Pharmaceutical Solutions products

EmulSol is a technology for production of oil-in-water nano-emulsions.  Nano-emulsions have droplet sizes in the range of 50 to 500 nanometers, and are stable for the intended shelf-life of the product.  Ascendia® produces nano-emulsions using a high-shear homogenization process.  After a suitable oil phase is chosen (based on chemical compatibility and solubility with the drug substance), a mixture of the oil, water, and the drug substance is processed through the homogenizer creating a fine suspension of the oil droplets in a water phase.  As the drug substance is significantly more soluble in the oil phase, than in the water phase, the vast majority of the drug is solubilized within the interior of the oil droplets.  Thus when the nano-emulsion is delivered to the body, the drug substance is more readily bioavailable.