Aura Industries Inc. articles

Abstract

High throughput purification techniques are an important part of drug discovery and provide high-quality compounds for biological screening. In this paper, we describe the purification platform developed by ArQule that is based on reverse phase high performance liquid chromatography (RP-HPLC) separation and mass directed fractionation. By strictly enforcing collection of only one fraction per sample, this purification paradigm has significantly enhanced the t