Avelas Biosciences products

Pegloprastide (AVB-620) is based on the science of activatable cell-penetrating peptides and is designed to deliver a fluorescent marker specifically to cancer cells to enable surgeons to identify cancerous tissue in real-time and thus, avoid repeat surgeries and improve patient outcomes. Pegloprastide is the only fluorescence-based clinical cancer detection product that uses the ratio of two fluorophores within the same molecule (ratiometric imaging) to provide more accurate and actionable information during a procedure.

Avelas’ Intraoperative Imaging Device simultaneously images two far red and near infra-red wavelengths to realize the advantages of ratiometric fluorescent readout of pegloprastide for real-time cancer detection.