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BacVax - Commercial Bacterial Vaccines
Current commercial bacterial vaccines use toxin neutralization, capsule targeting, or multiple proteins. While these methods may work in some circumstances, many bacteria do not have toxin or capsule targets, and using several proteins in a vaccine is expensive and opens the opportunity for genetic escape by the bacteria.
BacVax - The Alternative to Antibiotics
Antibiotics are currently the main defense against bacterial infections, but every treatment with antibiotics has unintended consequences. First, antibiotic-resistant mutants of the bacteria targeted by treatment may be selected. Second, the by-stander bacteria, for example in the GI tract, are also exposed to antibiotics and may become resistant. Third, the microbiome is significantly disturbed by antibiotics, and we continue to learn how important the microbiome is for general health.
