Base4
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Base4 - Exploiting RNA Structural Dynamics

Leading the RNA ensemble revolution. Exploiting RNA dynamics: RNAs rapidly exchange between a vast array of distinct 3D conformations, each revealing potentially novel binding surfaces. These dynamics are critical to understanding RNA function and fully exploiting its untapped drug potential. Our proprietary platform is built on unparalleled advancements in RNA structural biology that allows for the visualization of RNA dynamics at the atomic level with unprecedented sensitivity, enabling the targeting of potentially hidden druggable conformations.