BCN Peptides S.A. products

Alarelin is a synthetic polypeptide which acts as LH-RH (Luteinizing-hormone releasing hormone) analogue agonist. LH-RH is secreted in the hypothalamus and its release induces the secretion of LH (Luitenizing hormone) and FSH (Follicle-stimulating hormone) from the pituitary gland. These two hormones act on the ovaries and the testes and are responsible of the profertility effects of LHRH through the release of steroideal hormones. The biological activity of Alarelin, a synthetic LH-RH agonist, is dozens of times higher than that of LH-RH in the test of rat hypophyseal stimulation of gonadotropin secretion in vivo and in vitro and in the ovulation induction test.

Arginine Vasopressin is a form of vasopressin obtained from most of mammals including man but excluding pig. It is usually prepared synthetically. It has a direct antidiuretic action on the kidney, increasing tubular reabsortion of water. It also constricts peripheral blood vessels and causes contraction of the smooth muscle of the intestine, gallbladder and urinary bladder.

Angiotensin II is a vasoconstrictor used to increase blood pressure in adults with septic or other distributive shock. Angiotensin II is a naturally occurring hormone secreted as part of the renin-angiotensin system that results in powerful systemic vasoconstriction.

Abaloparatide is 34 amino acid synthetic analog of parathyroid hormone-related protein (PTHrP) (1-34). It works as an anabolic agent for the bone, through selective activation of the parathyroid hormone 1 receptor (PTH1R), a G protein-coupled receptor (GPCR) expressed in the osteoblasts and osteocytes.

Adrenocorticotropic hormone (ACTH), also known as corticotropin, is a polypeptide tropic hormone produced and secreted by the anterior pituitary gland. It is the major regulator of the adrenal cortex function. It is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress (along with its precursor corticotropin-releasing hormone from the hypothalamus). Its principal effects are increased production and release of corticosteroids. A deficiency of ACTH is a cause of secondary adrenal insufficiency and an excess of it is a cause of Cushing’s syndrome.