Beijing Biosis Healing Biological Technology Co., Ltd. products

The Biological Dental Membrane, developed by Biosis Healing, is crafted from an extracellular matrix-derived biomaterial known as SIS. This membrane features a natural fibrous porosity and is abundant in bioactive substances, enhancing its biological inductive activity. It facilitates tissue regeneration by promoting rapid vascularization, cell differentiation, and mucosal crawling. The membrane integrates seamlessly with host tissues upon implantation, ensuring bioactivity preservation and bioactive factor release. It is processed to remove immunogenic substances, making it highly compatible with tissues and malleable, thus comfortably adhering to soft tissues. Furthermore, it degrades and absorbs naturally within the body, leaving no residues. This membrane plays a critical role in dental surgeries, especially in bone grafting applications, by covering defective tissues and accelerating their repair and reconstruction.

The Biosis Healing Biological Hernia Graft is designed specifically for hernia repair using a highly specialized porcine small intestinal submucosa material (SIS material). The graft undergoes rigorous processing involving virus inactivation, decellularization, and sterilization with ethylene oxide, ensuring it is safe and effective for medical use. The SIS material is tailored to remove immunogenic substances while preserving its natural extracellular matrix structure, crucial for tissue regeneration. Notably, the non-crosslinking process and immunogen elimination technology minimize complications like inflammation and surgical recurrence. The product supports robust tissue regeneration, with active substance retention, such as FN content at 43%, and an α-GAL clearance rate of 3.8 ng/mg. The graft degrades completely, aiding in tissue integration and regeneration, and is suitable for various abdominal hernia repair procedures.

The Biosis Healing Dural Repair Patch is specifically designed to address and repair defects in the dura mater, the outermost membrane protecting the brain and spinal cord. Composed of a decellularized submucosal matrix derived from porcine small intestine submucosa, this patch is crafted through a non-crosslinking process which ensures that it can be effectively degraded and absorbed within the body. Its three-dimensional, loose, and porous structure is rich in bioactive components, allowing for the removal of immunogenic substances while retaining essential growth factors, adhesion proteins, and proteoglycans. These attributes support the natural healing process by maintaining the extracellular matrix's integrity. Its application is crucial in neurosurgery for repairing damages to the dura mater caused by trauma, infections, or surgeries, helping to avert complications such as cerebrospinal fluid leaks and reducing infection risks, thereby ensuring optimal patient recovery.

The SIS Wound Repair Matrix is a technologically advanced biomaterial designed for efficient wound management and tissue repair. It's derived from porcine small intestinal submucosa (SIS) and maintains an intact three-dimensional extracellular matrix structure crucial for tissue regeneration. This non-crosslinking biomaterial retains vital bioactive components such as collagen, elastin, glycosaminoglycans, glycoproteins, and proteoglycans, which are key for promoting healing processes in complex wounds including ulcers, surgical wounds, and various traumas. The product features strong hydrophilicity and is ready to use without hydration. It offers versatility with a range of sizes, accommodating varying wound depths and types. Anti-inflammatory and effectively devoid of DNA residuals, this product ensures biocompatibility and safety. With a two-year shelf life at room temperature, it promises convenience and efficacy for both medical professionals and patients.