BioMedica Diagnostics products

ACTICHROME Heparin (Anti-FIIa) is an in vitro diagnostic three-stage assay. It begins with plasmas containing heparin interacting with human antithrombin III to form a heparin-ATIII complex. In the second stage, thrombin is added, which the complex inhibits. The third stage involves the residual thrombin activity hydrolyzing SPECTROZYME TH, a chromogenic substrate. This design ensures that the measured thrombin activity is inversely proportional to the plasma heparin concentration. The assay uses bovine thrombin and a specific human antithrombin III reagent, making it a suitable choice for evaluating thrombin inhibition in clinical anticoagulation settings. It is noted for its compliance with CE Marking, FDA 510(K) clearance, and Health Canada registration standards.