Biorbyt Ltd products

Monoclonal antibodies; one of the most widely used tools in biological research, with the potential soon to become important therapeutics, have been with us for just over 40 years. These antibodies are monovalent, bind to a single epitope and are produced by a single B-lymphocyte clone. The first monoclonal antibody was generated in mice in 1975 by Milstein and Kohler, using the hybridoma technique.

Plasma cells are specialised B lymphocytes that secrete antibodies (glycoproteins) in response to infection by antigens (toxins or foreign substances). Antibodies, also known as immunoglobulins (Ig), usually have a high affinity to a specific antigen, binding only to one epitope/binding site on an antigen. Monoclonal (Mab) or polyclonal (pAb) antibodies are used in scientific research for a wide range of applications. This article will guide your choice for your research.