95 services found

CD Formulation services

CD Formulation - Preformulation

Preformulation is an investigation of physical and chemical properties of a drug substance when used alone or combined with excipients. Early prediction of these properties will generate information useful to the formulator in developing stable and safe dosage forms with good bioavailability. At CD Formulation , our preformulation services are equipped with advanced instrumentation, and our research team not only have the expertise to handle the most complex formulations, but also have a depth of experience in the pharmaceutical industry and contract service organisations. CD Formulation can offer tailored and rational preformulation development. https://www.formulationbio.com/preformulation.html

CD Formulation - LogP/LogD/pKa Analysis

CD Formulation can provide you with LogP/LogD/pKa analysis services of APIs and inactive ingredients, and the pKa testing will be performed by our scientists through calculating the LogP or LogD values and measured in various pH values. It will help you to make a decision for operational and procedural conditions that can ensure the physical and chemical stability and pharmacological activity of the product to minimize potential formulation and stability issues. More at https://www.formulationbio.com/logp-logd-pka-analysis.html

CD Formulation - Solubility Analysis

CD Formulation can provide you with dissolution profiles of active pharmaceutical ingredients in various solvents (including inorganic solvents with different pH values, organic solvents, simulated intestinal juice or gastric juice, and other solvents) according to your needs. In addition, our scientists specialize in providing solubility enhancement services through a variety of technologies and methods to minimize potential formulation and stability issues. Learn more at https://www.formulationbio.com/solubility-analysis.html Our Solubility Analysis Services Building a full range pH solubility profile Solubility in simulated gastrointestinal media Solubility improvement

CD Formulation - Stability Analysis

Stability analysis is a very interesting field in pre-formulation research. Under the influence of various environmental factors (such as temperature, humidity, and light), the stability of active pharmaceutical ingredients (API) or the stability of pharmaceutical products is evaluated. This is helpful to study the internal stability of candidate drug molecules and obtain useful information, it is important to improve the integrity of pharmaceutical products and prevent changes in their physical, chemical and pharmacological properties. CD Formulation can provide you with stability analysis services of active ingredients and excipients, and our scientists will help you to make a decision for operational and procedural conditions that can ensure the physical and chemical stability and pharmacological activity of the product to minimize potential formulation and stability issues. Learn more at https://www.formulationbio.com/stability-analysis.html

CD Formulation - Solubility Improvement and Bioavailability Enhancement Services for Drug Design

Bioavailability refers to the degree and speed at which a drug is absorbed into the blood circulation. There are ongoing challenges with poorly water-soluble drugs and have failed to reach the market due to their poor water solubility. CD Formulation has developed a range of technologies and formulation expertise to improve the solubility and bioavailability of these drugs, helping customers find the right way to commercialize their drug products. This experience, along with a variety of techniques, enables CD Formulation to overcome many of the hurdles surrounding solubility and bioavailability, including physical, chemical, encapsulation techniques and so on. Learn more at https://www.formulationbio.com/solubility-improvement-and-bioavailability-enhancement-services.html

CD Formulation - API Physical Modification Services for Drug Development

At present, many drugs are often lower than the concentration required for treatment due to their low solubility, even in saturated solutions. For example, the solubility of chloramphenicol in water is 0.25%, and clinically, more than 12.5% solution is required for intramuscular or intravenous injection. In the pharmaceutical liquid preparation industry, it is necessary to increase the solubility of certain drugs. There are many ways to increase the solubility of drugs, and each has its own advantages. Among them, physical treatment is a very common way. CD Formulation enhances the bioavailability and solubility of drugs through API physical modification services, including nanomilling, micronization, co-crystals, amorphous solutions and dispersions and other technical services. Learn more at https://www.formulationbio.com/api-physical-modification-services.html

CD Formulation - API Chemical Modification Services for Drug Development

Industry estimates indicate that over 80% of new chemical entities exhibit low solubility, low bioavailability, and/or low or inconsistent dissolution rates. Effectively addressing these drug solubility, bioavailability, and dissolution rate issues is critical to advancing compound development and providing patients with the therapeutic benefits needed for pharmaceutical products. The Enhanced Bioavailability services provided by CD Formulation make us a leader in addressing issues of low solubility, low bioavailability and dissolution rates. Our end-to-end enhancement solutions combine the full capability to take a compound from concept to commercialization, minimizing project complexity, timelines and risk. Learn more at https://www.formulationbio.com/api-chemical-modification-services.html

CD Formulation - Encapsulation Techniques Services for Drug Development

Solubility and bioavailability issues run through drug metabolism and pharmacokinetic evaluation of candidate compounds, preclinical prescription development, and commercial formulation development. From the toxicological evaluation stage, CD Formulation has a perfect drug metabolism and pharmacokinetic support system, each experiment only consumes milligram-level API, which can help customers select the most suitable solvent for animal experiments in the early stage and shorten the development cycle. In the development of commercial formulations, CD Formulation is familiar with a variety of industrially scalable and enhanced bioavailability drug delivery methods and can use the most scientific and efficient platform technology to rapidly advance the formulation concept from milligram-level high-throughput experiments to production-level. More at https://www.formulationbio.com/encapsulation-techniques-services.html

CD Formulation - API Physical Modification

Bioavailability of active pharmaceutical ingredients (APIs) is a key factor in successful drug development. By choosing API physical modification services, we can support your solution, improve poor water solubility, and control optimized release characteristics to help increase your productivity and return on investment. Nanomilling to Prepare Small Particle Size Drug Particles Services Micronization Technical Services Forming Co-crystals Services Amorphous Solutions and Dispersions Technical Services Liquid-Solid Compression Services Learn more at https://www.formulationbio.com/api-physical-modification-services.html