LEVERAGING THE POWER OF EVOLUTION

At cellvie, we are pioneering Therapeutic Mitochondria Transplantation, a novel treatment approach aimed at the cellular energy metabolism. We are deriving medicines from cells, leveraging one of the cornerstones of evolution: mitochondria.

TO SAVE AND RESTORE

Mitochondria are the powerhouses of the cell. cellvie is employing Therapeutic Mitochondria Transplantation, a technique of augmentation and replacement to reinvigorate the cell energy metabolism when the mitochondria are failing. The first application will be in ischemia-reperfusion injury, the world`s number 1 killer.

MITOCHONDRIA ARE INTIMATELY TIED TO THE ORIGIN OF COMPLEX LIFE

Mitochondria are membrane-bound cell organelles that generate most of the energy needed to power the cell`s biochemical reactions. In a process referred to as symbiogenesis, mitochondria are said to have merged with a simple cellular organism, giving rise to complex life and its evolution. In this process, Mitochondria took over vital roles within the cell, including:

ISCHEMIA-REPERFUSION INJURY

cellvie is targeting ischemia-reperfusion injury as its technology`s first application. Ischemia-Reperfusion is a ubiquitous challenge, arising whenever blood flow is interrupted and subsequently re-introduced. Medical conditions giving rise to ischemia-reperfusion injury are heart attacks, stroke, long surgical procedures and organ transplantation.

The first indication will be in kidney transplantation. With 12 patients dying each day waiting for a kidney, the need is particularly dear. The aim is to reduce the incidence of delayed graft function, which arises in up to 50% of kidney recipients.

EMERGENCE OF A NEW TREATMENT MODALITY

With mitochondria a common denominator in health as well as in disease and aging, cellvie strives to bring about Therapeutic Mitochondria Transplantation as a novel category of medicines. The approach`s ability to sustainably affect the cell-energy-metabolism opens new avenues to treat hitherto intractable human conditions.

Beyond ischemia-reperfusion injury, the team at cellvie is particularly interested in the technology`s application to slow or reverse degenerative processes of aging linked to the mitochondria.

cellvie Inc. products

cellvie - Mitochondria Therapy