Cercare Medical A/S articles

Introduction
Neurologic complications are frequently reported in COVID-19, but our understanding of their pathophysiologic causes and neuroanatomical correlates is limited.

While several structural brain imaging findings have been reported in COVID-19, including non-spherical signal abnormalities on Susceptibility-Weighted Imaging (SWI), conventional perfusion imaging has not provided consistent insights into brain tissue status in patients with long COVID-19.

Introduction
Moyamoya disease (MMD) is a cerebrovascular disease characterised by progressive steno-occlusion of the terminal part of the internal carotid arteries, causing a decline in cerebral perfusion pressure (CPP) distal to the steno-occlusion lesion.

This will trigger a haemodynamic and metabolic response to preserve the cerebral metabolic rate of oxygen (CMRO2). Cerebral auto-regulation will dilate resistance arteries to maintain adequate cerebral blood f