Creative Biostructure articles

Exosomes, small vesicles released by cells, play an increasingly prominent role in intercellular communication and disease modulation. These nano-sized particles contain a diverse array of molecular cargo, including proteins, lipids, RNA, and metabolites, which serve as biomarkers for a variety of physiological conditions. Exosome lipidomics and metabolomics are key fields that focus on profiling the lipids and metabolites present in exosomes. Together, these studies offer a deeper understand

Liposomes, spherical vesicles composed of one or more phospholipid bilayers, have garnered significant attention in the field of drug delivery due to their unique properties. These nanocarriers offer a promising approach to overcome challenges associated with traditional drug administration, enhancing therapeutic efficacy while minimizing side effects. This article will delve into the role of liposomes in drug delivery, highlighting progress made and the limitations that remain, as well as ex

Introduction

Within the intricate world of cellular biology, membrane scaffold proteins play a crucial role in maintaining the structural integrity and functionality of cell membranes. These proteins act as building blocks, providing support and stability to the delicate lipid bilayer that surrounds and protects the cell. In this blog post, we will explore the fascinating world of membrane scaffold proteins, their functions, and their significance in cellular architecture

Imagine tiny spheres, smaller than a red blood cell, glowing as they navigate the labyrinthine corridors of the human body. These aren't fireflies, they're fluorescent liposomes, a cutting-edge tool in the world of drug delivery and biomedical research.

What are liposomes?

Liposomes are microscopic bubbles made from phospholipids, the same fatty molecules that make up cell membranes

Imagine tiny bubbles, smaller than a red blood cell, carrying powerful medicines directly to diseased cells. This isn't science fiction, it's the cutting edge of drug delivery with drug-loaded liposomes.

What are liposomes?

Liposomes are microscopic spheres made from phospholipids, the same fatty molecules that make up cell membranes. These phospholipids naturally arrange themselves

Nano-flow cytometry is a revolutionary technology that has the potential to transform early disease detection and diagnosis. Nano-flow cytometers are able to detect and analyze individual nanoparticles, including extracellular vesicles and viruses, with high sensitivity and accuracy. This makes them ideal for detecting diseases at their earliest stages, when they are most treatable.

How does nano-flow cytometry work?

In nano-flow cytometry (

A team of scientists from around the world, including from Trinity College Dublin, has obtained high-resolution structural insights into a key bacterial enzyme, which may help chemists design new drugs to inhibit it, thereby inhibiting disease-causing bacteria. Their work is important amid growing concerns about rising antibiotic resistance.

The scientists, led by Martin Caffrey, Emeritus Fellow of Trinity's Faculty of Medicine and School of Biochemistry and Immunology, u

Fluorescent substance and fluorescent labeling technology

The compounds upon which fluorescent labeling depends are called fluorescent substances. Fluorescent substances refer to compounds with a conjugated double bond system chemical structure, which can be excited into an excited state when irradiated by ultraviolet light or blue-violet light, and emit fluorescence when returning to the ground state from the excited state.

Fluorescent labeling technology refers t

Gene editing is one of the latest breakthroughs in biology. The well-known CRISPR-Cas gene editing system confers immunity against foreign DNA to prokaryotes (organisms lacking a cell nucleus). Since the discovery of CRISPR gene editing technology, scientists have revealed how CRISPR-cas proteins evolved from their precursors. This knowledge will help them develop other small new genome editing tools for gene therapy.

At the University of Tokyo, Professor Osamu Nureki's t

Scientists from Rutgers University and Salk Institute have determined the molecular structure of HIV Pol polyprotein, which plays a key role in helping the virus spread itself and systemically. This finding may stimulate new treatments for more than 40 million AIDS patients worldwide.

 Their findings, published in Science Advances, could guide the development of drugs that bind to the protein and block its function.

 "Drug molecules require a specific structure to sp