Cresset Group news
Atomistic simulations constitute one of the primary uses of high-performance computing in research, as they establish the foundation of Research and Development procedures in the chemical and biological sectors. Among the plethora of open-source academic software, OpenMM has the quickest rate of growth due to its excellent tradeoff between extensibility via a robust user interface, and performance on GPUs. This has caused the OpenMM user base, which was initially focused on the biomolecular s
Antibodies (immunoglobulins) are a key component of the mammalian immune response and are increasingly of interest as a means of therapy for several diseases. In fact, there are over 100 monoclonal antibodies that have been approved as drugs1. Despite this apparent success, there are issues with biopharmaceutical antibody research and development – not least the cost of goods. Although it can be argued that therapeutic antibody development relies on semi-random search-a
The field of protein DNA/RNA interactions is an expanding area of research. These interactions affect fundamental processes and as a result, relevant protein DNA/RNA processing complexes and their associated mechanisms provide interesting therapeutic targets to researchers. However, due to the complex and often delicate nature of these systems, traditionally researchers haven’t had sufficient tools to address them.