CrystalsFirst GmbH services

Crystalsfirst Unlocks Chemical Matter On Scale By Putting Structural Data First. We have developed technologies that overcome current limitations of small molecule drug discovery. The integration of our high-performance structural biology, compound libraries with computational chemistry capabilities identifies novel molecules and druggable binding pockets for difficult targets.

We also provide consulting services for the target-to-hit phase and structurally-enabled campaigns. Our cutting-edge solutions, collaborative culture, speed and agility, enable us to move with you in the direction, that will best suit your quest for success. Fragment-based drug design relies heavily on the availability of structural data for fragment growth into a lead candidate. Based on our track record in structural biology, we can support your campaigns by applying our proprietary know-how for de-risking the projects. For example, not every crystal packing is suitable for co-structure determination by X-ray crystallography. We offer packing analyses and soakability assessments to ensure the compatibility of the crystals and ligands for co-structure determination.